Chemistry:Diffractaic acid

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Short description: Chemical compound produced by lichens
Diffractaic acid
Diffractaic acid.svg
Names
IUPAC name
4-(2,4-dimethoxy-3,6-dimethylbenzoyl)oxy-2-hydroxy-3,6-dimethylbenzoic acid[1]
Other names
Diffractic acid,[1] Dirbizomic acid,[1] Dirhizomic acid,[1] NSC 5901[2],NSC 685595[2]
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
Properties
C20H22O7
Molar mass 374.389 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):

Diffractaic acid is a β-orcinol depside with the molecular formula C20H22O7, which is produced by lichens.[3][1][4] Diffractaic acid has cytotoxic, cytogenetic, oxidative, analgesic and antiviral effects.[4]

The foliose lichen species Punctelia diffractaica is named for the presence of this compound.[5]

References

  1. 1.0 1.1 1.2 1.3 1.4 "Diffractaic acid" (in en). Pubchem.ncbi.NLM.nih.gov. https://pubchem.ncbi.nlm.nih.gov/compound/Diffractaic-acid#section=Names-and-Identifiers. 
  2. 2.0 2.1 2.2 (in en) Diffractaic Acid (CAS 436-32-8). https://www.caymanchem.com/product/24208. 
  3. Sukumaran, Swapna Thacheril; Sugathan, Shiburaj; Abdulhameed, Sabu (28 November 2020) (in en). Plant Metabolites: Methods, Applications and Prospects. Springer Nature. p. 265. ISBN 978-981-15-5136-9. 
  4. 4.0 4.1 Demir, Leyla; Toğar, Başak; Türkez, Hasan; Sozio, Piera; Aslan, Ali; Stefano, Antonio Di (2015). "The investigation of cytogenetic and oxidative effects of diffractaic acid on human lymphocyte cultures" (in en). Brazilian Archives of Biology and Technology 58: 75–81. doi:10.1590/S1516-8913201502752. ISSN 1516-8913. 
  5. Kurokawa, S. (1999). "Notes on Flavopunctelia and Punctelia (Parmeliaceae), with descriptions of four new species". Bulletin of the Botanical Garden of Toyama 4: 25–32. 

Further reading

  • Sinha, Rajeshwar P.; Häder, h c Donat-P. (6 October 2020) (in en). Natural Bioactive Compounds: Technological Advancements. Academic Press. p. 257. ISBN 978-0-12-820659-1.