Chemistry:Fletikumab

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Short description: Monoclonal antibody
Fletikumab
Monoclonal antibody
Type?
TargetIL20
Clinical data
Other namesNNC0109-0012
ATC code
  • none
Identifiers
CAS Number
ChemSpider
  • none
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC6494H10000N1728O2050S44
Molar mass146492.12 g·mol−1

Fletikumab (NNC0109-0012) (INN[1]) is a monoclonal antibody designed for the treatment of rheumatoid arthritis[2] that targets IL-20.[3]

This drug was being developed by Novo Nordisk A/S until Novo ceased work in inflammation.

References

  1. ↑ World Health Organization (2013). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 110". WHO Drug Information 27 (4). https://www.who.int/medicines/publications/druginformation/innlists/PL111.pdf. 
  2. ↑ Statement On A Nonproprietary Name Adopted By The USAN Council - Fletikumab, American Medical Association.
  3. ↑ "The IL-20 Cytokine Family in Rheumatoid Arthritis and Spondyloarthritis". Frontiers in Immunology 9: 2226. 2018. doi:10.3389/fimmu.2018.02226. PMID 30319661. 




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