Chemistry:2-Aminopurine
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| Preferred IUPAC name
9H-Purin-2-amine | |
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3D model (JSmol)
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| Properties | |
| C5H5N5 | |
| Molar mass | 135.130 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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Tracking categories (test):
2-Aminopurine, a purine analog of guanine and adenine, is a fluorescent molecular marker used in nucleic acid research.[1] It most commonly pairs with thymine as an adenine-analogue, but can also pair with cytosine as a guanine-analogue.[2] For this reason it is sometimes used in the laboratory for mutagenesis.
See also
- Nucleic acid analogues
References
- ↑ "2-Aminopurine fluorescence quenching and lifetimes: role of base stacking". Proc. Natl. Acad. Sci. U.S.A. 98 (1): 37–41. 2001. doi:10.1073/pnas.011442198. PMID 11120885. PMC 14540. http://www.pnas.org/cgi/pmidlookup?view=long&pmid=11120885.
- ↑ "Base pairing and mutagenesis: observation of a protonated base pair between 2-aminopurine and cytosine in an oligonucleotide by proton NMR". Proc. Natl. Acad. Sci. U.S.A. 83 (15): 5434–5438. 1986. doi:10.1073/pnas.83.15.5434. PMID 3461441. Bibcode: 1986PNAS...83.5434S.
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