Biology:MAP3K9

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

Mitogen-activated protein kinase kinase kinase 9 is an enzyme that in humans is encoded by the MAP3K9 gene.

Further reading

• "Identification and characterization of SPRK, a novel src-homology 3 domain-containing proline-rich kinase with serine/threonine kinase activity.". J. Biol. Chem. 269 (21): 15092–100. 1994. doi:10.1016/S0021-9258(17)36578-X. PMID 8195146. 
• "Identification of a new family of human epithelial protein kinases containing two leucine/isoleucine-zipper domains.". Eur. J. Biochem. 213 (2): 701–10. 1993. doi:10.1111/j.1432-1033.1993.tb17810.x. PMID 8477742. 
• "Complete nucleotide sequence, expression, and chromosomal localisation of human mixed-lineage kinase 2.". Eur. J. Biochem. 234 (2): 492–500. 1996. doi:10.1111/j.1432-1033.1995.492_b.x. PMID 8536694. 
• "The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis.". Mol. Cell. Biol. 21 (14): 4713–24. 2001. doi:10.1128/MCB.21.14.4713-4724.2001. PMID 11416147. 
• "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M. 
• "Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex.". J. Biol. Chem. 278 (48): 47922–7. 2004. doi:10.1074/jbc.M307357200. PMID 14504284. 
• "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039. 
• "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334. 
• "Phosphoregulation of mixed-lineage kinase 1 activity by multiple phosphorylation in the activation loop.". Biochemistry 43 (51): 16348–55. 2005. doi:10.1021/bi049866y. PMID 15610029. 

External links

• Overview of all the structural information available in the PDB for UniProt: P80192 (Mitogen-activated protein kinase kinase kinase 9) at the PDBe-KB.