Biology:LMLN

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

Leishmanolysin-like (metallopeptidase M8 family) is a protein that in humans is encoded by the LMLN gene.

Function

This gene encodes a zinc-metallopeptidase. The encoded protein may play a role in cell migration and invasion. Studies of a similar protein in Drosophila indicate a potential role in mitotic progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009].

Further reading

• "The conserved metalloprotease invadolysin localizes to the surface of lipid droplets". Journal of Cell Science 122 (Pt 18): 3414–23. September 2009. doi:10.1242/jcs.044610. PMID 19706689. 
• "Invadolysin: a novel, conserved metalloprotease links mitotic structural rearrangements with cell migration". The Journal of Cell Biology 167 (4): 673–86. November 2004. doi:10.1083/jcb.200405155. PMID 15557119. 

This article incorporates text from the United States National Library of Medicine, which is in the public domain.