Biology:SERPINB7

Generic protein structure example

Serpin B7 is a protein that in humans is encoded by the SERPINB7 gene.

See also

• Serpin

Further reading

• "Purification, cDNA cloning, and characterization of a new serpin with megakaryocyte maturation activity.". J. Biol. Chem. 272 (24): 15373–80. 1997. doi:10.1074/jbc.272.24.15373. PMID 9182567. 
• "A mesangium-predominant gene, megsin, is a new serpin upregulated in IgA nephropathy.". J. Clin. Invest. 102 (4): 828–36. 1998. doi:10.1172/JCI2450. PMID 9710452. 
• "Specific tissue distribution of megsin, a novel serpin, in the glomerulus and its up-regulation in IgA nephropathy.". Biochem. Biophys. Res. Commun. 286 (5): 1098–106. 2001. doi:10.1006/bbrc.2001.5509. PMID 11527413. 
• "Mesangial cell-predominant gene, megsin.". Nephrol. Dial. Transplant. 17 Suppl 9 (90009): 32–3. 2003. doi:10.1093/ndt/17.suppl_9.32. PMID 12386281. 
• "Transcriptional regulation of a mesangium-predominant gene, megsin.". J. Am. Soc. Nephrol. 13 (11): 2715–22. 2003. doi:10.1097/01.ASN.0000033507.32175.FA. PMID 12397041. http://jasn.asnjournals.org/content/13/11/2715.full.pdf. 
• "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M. 
• "Family-based association study showing that immunoglobulin A nephropathy is associated with the polymorphisms 2093C and 2180T in the 3' untranslated region of the Megsin gene.". J. Am. Soc. Nephrol. 15 (7): 1739–43. 2004. doi:10.1097/01.ASN.0000130858.00688.46. PMID 15213261. 
• "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.". Genome Res. 14 (9): 1711–8. 2004. doi:10.1101/gr.2435604. PMID 15342556. 
• "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334. 
• "Novel serpinopathy in rat kidney and pancreas induced by overexpression of megsin.". J. Am. Soc. Nephrol. 16 (5): 1339–49. 2005. doi:10.1681/ASN.2004070600. PMID 15788472. 
• "Association of MEGSIN 2093C-2180T haplotype at the 3' untranslated region with disease severity and progression of IgA nephropathy.". Nephrol. Dial. Transplant. 21 (6): 1570–4. 2006. doi:10.1093/ndt/gfk096. PMID 16431886. 
• "A family-based association study of megsin A23167G polymorphism with susceptibility and progression of IgA nephropathy in a Chinese population.". Clin. Nephrol. 65 (3): 153–9. 2006. doi:10.5414/cnp65153. PMID 16550745. 

External links

• The MEROPS online database for peptidases and their inhibitors: I04.012
• SERPINB7+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.