Medicine:Michelin tire baby syndrome
| Michelin tire baby syndrome | |
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| Specialty | Dermatology |
Michelin tire baby syndrome (also known as Kunze–Riehm syndrome[1] and "folded skin with scarring"[2]:625), is a condition occurring in babies that is characterized by multiple, symmetric, circular skin creases, or bands, on the forearms, lower legs, and often the neck that are present at birth. The creases disappear later in life. They are reminiscent of those of Bibendum, the mascot of the tire manufacturer Michelin, hence the name of the syndrome. Associated abnormalities vary and may include facial dysmorphism, upslanting palpebral fissures, hypertelorism, cleft palate, genital anomalies, mild developmental delay, ureterocele, smooth muscle hamartoma, nevus lipomatosus, Laron syndrome (dwarfism with high growth hormone and low somatomedin activity), and other defects.
It was originally described by Ross in 1969.[3]
See also
- List of cutaneous conditions
Notes
- ↑ Ramphul, Kamleshun; Mejias, Stephanie G; Ramphul-Sicharam, Yogeshwaree (2018). "A Rare Case of Michelin Tire Baby Syndrome in a Newborn". Cureus 10 (2): e2222. doi:10.7759/cureus.2222. ISSN 2168-8184. PMID 29696100.
- ↑ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN:0-7216-2921-0.
- ↑ Ross CM (September 1969). "Generalized folded skin with an underlying lipomatous nevus. "The Michelin Tire baby"". Arch Dermatol 100 (3): 320–3. doi:10.1001/archderm.100.3.320. PMID 4980758. http://archderm.ama-assn.org/cgi/pmidlookup?view=long&pmid=4980758.[yes|permanent dead link|dead link}}]
References
- "Michelin tire baby syndrome: familial constriction bands during infancy and early childhood in four generations". Am J Med Genet 45 (3): 370–2. February 1993. doi:10.1002/ajmg.1320450318. PMID 8434626.
- "Variability in the Michelin tire syndrome. A child with multiple anomalies, smooth muscle hamartoma, and familial paracentric inversion of chromosome 7q". J Am Acad Dermatol 28 (2 Pt 2): 364–70. February 1993. doi:10.1016/0190-9622(93)70056-Y. PMID 8436660.
- "Circumferential ringed creases ('Michelin tire babies') with specific histologic findings and/or karyotype abnormalities: clues to molecular pathogenesis?". Am J Med Genet 69 (2): 221. March 1997. doi:10.1002/(SICI)1096-8628(19970317)69:2<221::AID-AJMG22>3.0.CO;2-M. PMID 9056567.
- "Hypertrichosis, pigmentary retinopathy, and facial anomalies: a new syndrome?". Am J Med Genet 62 (4): 386–90. April 1996. doi:10.1002/(SICI)1096-8628(19960424)62:4<386::AID-AJMG11>3.0.CO;2-K. PMID 8723069.
- "Folded skin with an underlying cutaneous smooth muscle hamartoma". Br J Dermatol 129 (5): 606–8. November 1993. doi:10.1111/j.1365-2133.1993.tb00495.x. PMID 8251362.
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