Physics:Jaktinib
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Jaktinib is a janus kinase inhibitor under development for myelofibrosis.[1][2] It is a deuterated-drug analog of momelotinib.[1]
References
- ↑ 1.0 1.1 Zhang, Yi; Zhou, Hu; Jiang, Zhongxing; Wu, Dengshu; Zhuang, Junling; Li, Wei; Jiang, Qian; Wang, Xiuli et al. (December 2022). "Safety and efficacy of jaktinib in the treatment of Janus kinase inhibitor-naïve patients with myelofibrosis: Results of a phase II trial". American Journal of Hematology 97 (12): 1510–1519. doi:10.1002/ajh.26709. ISSN 1096-8652. PMC 10092883. https://pubmed.ncbi.nlm.nih.gov/36054786/.
- ↑ Zhang, Yi; Zhou, Hu; Xiao, Zhi-Jian; Duan, Minghui; Gao, Sujun; He, Guangsheng; Jing, Hongmei; Li, Junmin et al. (2023). "Jaktinib in patients (pts) with myelofibrosis (MF) who were intolerant to ruxolitinib (RUX): An open-label, single-arm phase 2b study.". Journal of Clinical Oncology 41 (16_suppl): 7061–7061. doi:10.1200/JCO.2023.41.16_suppl.7061.
Original source: https://en.wikipedia.org/wiki/Jaktinib.
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