Chemistry:Psoromic acid
From HandWiki
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IUPAC name
10-Formyl-9-hydroxy-3-methoxy-4,7-dimethyl-6-oxobenzo[b][1,4]benzodioxepine-1-carboxylic acid[1]
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Other names
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Identifiers | |
3D model (JSmol)
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ChEBI | |
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ChemSpider | |
PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C18H14O8 | |
Molar mass | 358.302 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
Psoromic acid is a β-orcinol depsidone with the molecular formula C18H14O8. Psoromic acid inhibits herpes simplex viruses type 1 and type 2.[2] Furthermore, it inhibits the RabGGTase.[3] Psoromic acid occurs in antarctic lichens.[2][4]
References
- ↑ "Psoromic acid" (in en). Pubchem.ncbi.NLM.nih.gov. https://pubchem.ncbi.nlm.nih.gov/compound/Psoromic-acid.
- ↑ 2.0 2.1 Hassan, Sherif T. S.; Šudomová, Miroslava; Berchová-Bímová, Kateřina; Šmejkal, Karel; Echeverría, Javier (11 August 2019). "Psoromic Acid, a Lichen-Derived Molecule, Inhibits the Replication of HSV-1 and HSV-2, and Inactivates HSV-1 DNA Polymerase: Shedding Light on Antiherpetic Properties". Molecules 24 (16): 2912. doi:10.3390/molecules24162912. PMID 31405197.
- ↑ Deraeve, Céline; Guo, Zhong; Bon, Robin S.; Blankenfeldt, Wulf; DiLucrezia, Raffaella; Wolf, Alexander; Menninger, Sascha; Stigter, E. Anouk et al. (2 May 2012). "Psoromic Acid is a Selective and Covalent Rab-Prenylation Inhibitor Targeting Autoinhibited RabGGTase". Journal of the American Chemical Society 134 (17): 7384–7391. doi:10.1021/ja211305j. PMID 22480322.
- ↑ Sukumaran, Swapna Thacheril; Sugathan, Shiburaj; Abdulhameed, Sabu (28 November 2020) (in en). Plant Metabolites: Methods, Applications and Prospects. Springer Nature. p. 278. ISBN 978-981-15-5136-9.
Further reading
- Deraeve, Céline; Guo, Zhong; Bon, Robin S.; Blankenfeldt, Wulf; DiLucrezia, Raffaella; Wolf, Alexander; Menninger, Sascha; Stigter, E. Anouk et al. (2 May 2012). "Psoromic Acid is a Selective and Covalent Rab-Prenylation Inhibitor Targeting Autoinhibited RabGGTase". Journal of the American Chemical Society 134 (17): 7384–7391. doi:10.1021/ja211305j. PMID 22480322.
- (in en) Der Stoffwechsel Sekundärer Pflanzenstoffe / The Metabolism of Secondary Plant Products. Springer Science & Business Media. 11 November 2013. p. 592. ISBN 978-3-662-26784-4.
- (in en) Year-book of Pharmacy. J. & A. Churchill. 1883. p. 246.
- (in en) Issues in Chemistry and General Chemical Research: 2013 Edition. ScholarlyEditions. 1 May 2013. p. 323. ISBN 978-1-4901-0631-1.
![]() | Original source: https://en.wikipedia.org/wiki/Psoromic acid.
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