Chemistry:Tetrahydropapaveroline

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Tetrahydropapaveroline
Tetrahydropapaveroline.svg
Names
IUPAC name
1-[(3,4-dihydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol
Other names
Norlaudanosoline; Tetrahydroxypapaveroline
Identifiers
3D model (JSmol)
UNII
Properties
C16H17NO4
Molar mass 287.315 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):

Tetrahydropapaveroline (norlaudanosoline) is a benzyltetrahydroisoquinoline alkaloid.[1]

It can be formed in trace amounts in the brain by a condensation reaction of dopamine and dopaldehyde (a metabolite of dopamine).[1][2]

It inhibits dopamine uptake within the cerebral cortex.[citation needed]

References

  1. 1.0 1.1 Richter, Derek (14 October 2016) (in en). Addiction and Brain Damage. Routledge. p. 24. ISBN 978-1-315-45403-0. https://books.google.com/books?id=6MNCDQAAQBAJ&pg=PT24. 
  2. RD Myers; CL Melchior (29 Apr 1977). "Alcohol drinking: abnormal intake caused by tetrahydropapaveroline in brain". Science 196 (4289): 554–556. doi:10.1126/science.557839. PMID 557839. Bibcode1977Sci...196..554M.