Chemistry:Biflavonoid
From HandWiki
Biflavonoids are a type of flavonoids with the general formula scheme (C6-C3-C6)2.
Examples
- Amentoflavone (bis-apigenin coupled at 8 and 3' positions)
- Lophirone L and lophirone M found in Lophira alata
- Sulcatone A, a naturally occurring biflavonoid isolated from Ouratea sulcata. Extracts of the leaves of this plant, used with and with other plant's extracts, are used in many African countries to treat some infections such as upper tract respiratory infections, dysenteria, diarrhoea and toothache. Positive antimicrobial activity has been shown in-vitro against Staphylococcus aureus and Bacillus subtilis. Escherichia coli showed to be resistant in the same study.[1]
- Hinokiflavone, a cytotoxic biflavonoid from Toxicodendron succedaneum,[2] Juniperus sp.,[citation needed] or Chamaecyparis obtusa (hinoki).[3]
- Leaflets of Cycas circinalis and C. revoluta contain biflavonoids such as (2S, 2′′S)-2,3,2′′,3′′-tetrahydro-4′,4′′′-di-O-methylamentoflavone (tetrahydroisoginkgetin).[4]
- Agathisflavone[5][6]
- Cupressuflavone
- Ginkgetin
- Morelloflavone
- Neorhusflavanone
- Ochnaflavone
- Podocarpusflavone A
- Rhusflavone
- Rhusflavanone
- Robustaflavone
- Sciadopitysin
- Spicataside
- Succedaneaflavanone
- Volkensiflavone
- Moghatin, extracted from Glossostemon bruguieri [7]
References
- ↑ Pegnyemb, Dieudonné Emmanuel; Mbing, Josephine Ngo; de Théodore Atchadé, Alex; Tih, Raphael Ghogomu; Sondengam, Beiban Lucas; Blond, Alain; Bodo, Bernard (July 2005). "Antimicrobial biflavonoids from the aerial parts of Ouratea sulcata". Phytochemistry 66 (16): 1922–1926. doi:10.1016/j.phytochem.2005.06.017. PMID 16083925.
- ↑ Lin, Y. M.; Chen, F. C.; Lee, K. H. (April 1989). "Hinokiflavone, a cytotoxic principle from Rhus succedanea and the cytotoxicity of the related biflavonoids". Planta Med. 55 (2): 166–168. doi:10.1055/s-2006-961914. PMID 2526343.
- ↑ Krauze-Baranowska, M.; Pobłocka, L.; El-Hela, A. A. (September–October 2005). "Biflavones from Chamaecyparis obtusa". Z. Naturforsch. C 60 (9–10): 679–685. doi:10.1515/znc-2005-9-1004. PMID 16320608.
- ↑ Moawad, Abeer; Hetta, Mona; Zjawiony, Jordan K.; Jacob, Melissa R.; Hifnawy, Mohamed; Marais, Jannie P. J.; Ferreira, Daneel (2010). "Phytochemical investigation of Cycas circinalis and Cycas revoluta leaflets: Moderately active antibacterial biflavonoids". Planta Med. 76 (8): 796–802. doi:10.1055/s-0029-1240743. PMID 20072955.
- ↑ "Agathisflavone and GABAAreceptors in the biflavone-mediated action on rat primary cortical neurons". Neurotoxicology 66: 43–44. March 2018. doi:10.1016/j.neuro.2018.03.002. PMID 29530473.
- ↑ "Agathisflavone, a flavonoid derived from Poincianella pyramidalis (Tul.), enhances neuronal population and protects against glutamate excitotoxicity". Neurotoxicology 65: 85–97. February 2018. doi:10.1016/j.neuro.2018.02.001. PMID 29425760. https://researchportal.port.ac.uk/portal/en/publications/agathisflavone-a-flavonoid-derived-from-poincianella-pyramidalis-tul-enhances-neuronal-population-and-protects-against-glutamate-excitotoxicity(c0739f8a-b1da-429c-9cfb-a98a8f5e1cd6).html.
- ↑ Meselhy, Meselhy (31 July 2003). "Constituents from Moghat, the Roots of Glossostemon bruguieri (Desf.)" (in en-us). Molecules (MDPI) 8 (8): 614–621. doi:10.3390/80800614.
 |  |
