Biology:TOMM22
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Mitochondrial import receptor subunit TOM22 homolog is a protein that in humans is encoded by the TOMM22 gene.[1][2][3]
The protein encoded by this gene is an integral membrane protein of the mitochondrial outer membrane. The encoded protein interacts with TOMM20 and TOMM40, and forms a complex with several other proteins to import cytosolic preproteins into the mitochondrion.[3]
See also
References
- ↑ "Identification and functional analysis of human Tom22 for protein import into mitochondria". Mol Cell Biol 20 (19): 7205–13. Oct 2000. doi:10.1128/MCB.20.19.7205-7213.2000. PMID 10982837.
- ↑ "Identification of mammalian TOM22 as a subunit of the preprotein translocase of the mitochondrial outer membrane". J Biol Chem 275 (41): 31996–2002. Nov 2000. doi:10.1074/jbc.M004794200. PMID 10900208.
- ↑ 3.0 3.1 "Entrez Gene: TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56993.
Further reading
- "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1–2): 171–4. 1994. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. 1997. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- "Characterization of rat TOM40, a central component of the preprotein translocase of the mitochondrial outer membrane". J. Biol. Chem. 275 (48): 37930–6. 2001. doi:10.1074/jbc.M006558200. PMID 10980201.
- "Insertion and assembly of human tom7 into the preprotein translocase complex of the outer mitochondrial membrane". J. Biol. Chem. 277 (44): 42197–204. 2003. doi:10.1074/jbc.M205613200. PMID 12198123.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "AIP is a mitochondrial import mediator that binds to both import receptor Tom20 and preproteins". J. Cell Biol. 163 (1): 45–56. 2003. doi:10.1083/jcb.200305051. PMID 14557246.
- "Mitochondrial import receptors Tom20 and Tom22 have chaperone-like activity". J. Biol. Chem. 279 (11): 10808–13. 2004. doi:10.1074/jbc.M311710200. PMID 14699115.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. 2005. doi:10.1186/gb-2004-5-10-r84. PMID 15461802.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Dissection of the mitochondrial import and assembly pathway for human Tom40". J. Biol. Chem. 280 (12): 11535–43. 2005. doi:10.1074/jbc.M413816200. PMID 15644312.
- "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R.
- "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. 2006. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
- "TOM22, a core component of the mitochondria outer membrane protein translocation pore, is a mitochondrial receptor for the proapoptotic protein Bax". Cell Death Differ. 14 (4): 785–94. 2007. doi:10.1038/sj.cdd.4402055. PMID 17096026.
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