Biology:TOMM70A
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Mitochondrial import receptor subunit TOM70 is a protein that in humans is encoded by the TOMM70A gene.[1][2]
The translocase of outer mitochondrial membrane (TOM) complex is a multisubunit complex involved in the recognition, unfolding, and translocation of preproteins into the mitochondria. See TIM17A (MIM 605057).[supplied by OMIM][2]
See also
References
- ↑ "Identification of a mammalian homologue of the fungal Tom70 mitochondrial precursor protein import receptor as a thyroid hormone-regulated gene in specific brain regions". J Neurochem 73 (6): 2240–9. Dec 1999. doi:10.1046/j.1471-4159.1999.0732240.x. PMID 10582581.
- ↑ 2.0 2.1 "Entrez Gene: TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9868.
Further reading
- "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (5): 277–86. 1999. doi:10.1093/dnares/5.5.277. PMID 9872452.
- "Characterization of a human import component of the mitochondrial outer membrane, TOMM70A". Cell Commun. Adhes. 9 (1): 15–27. 2002. doi:10.1080/15419060212186. PMID 12200962.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Molecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70". Cell 112 (1): 41–50. 2003. doi:10.1016/S0092-8674(02)01250-3. PMID 12526792.
- "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Dissection of the mitochondrial import and assembly pathway for human Tom40". J. Biol. Chem. 280 (12): 11535–43. 2005. doi:10.1074/jbc.M413816200. PMID 15644312.
- "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. 2007. doi:10.1093/dnares/12.2.117. PMID 16303743.
- "An Internal EELD Domain Facilitates Mitochondrial Targeting of Mcl-1 via a Tom70-dependent Pathway". Mol. Biol. Cell 17 (9): 3952–63. 2006. doi:10.1091/mbc.E06-04-0319. PMID 16822835.
- "Hsp90 functions in the targeting and outer membrane translocation steps of Tom70-mediated mitochondrial import". J. Biol. Chem. 281 (44): 33313–24. 2006. doi:10.1074/jbc.M605250200. PMID 16968702.
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