Biology:UCA1
From HandWiki
Short description: Non-coding RNA in the species Homo sapiens
 Generic protein structure example |
In molecular biology, Urothelial cancer associated 1 (non-protein coding), also known as UCA1, is a long non-coding RNA, it is upregulated in bladder cancer.[1] It is believed to function in regulation of embryonic development and in bladder cancer invasion and progression. It regulates the expression of several genes involved in tumourgenesis and/or embryonic development.[2]
See also
- Long noncoding RNA
References
- ↑ "Rapid identification of UCA1 as a very sensitive and specific unique marker for human bladder carcinoma". Clinical Cancer Research 12 (16): 4851–8. 2006. doi:10.1158/1078-0432.CCR-06-0134. PMID 16914571. https://aacr.figshare.com/articles/journal_contribution/Supplementary_Tables_A-F_from_Rapid_Identification_of_UCA1_as_a_Very_Sensitive_and_Specific_Unique_Marker_for_Human_Bladder_Carcinoma/22441668/1/files/39892548.pdf.
- ↑ "UCA1, a non-protein-coding RNA up-regulated in bladder carcinoma and embryo, influencing cell growth and promoting invasion". FEBS Letters 582 (13): 1919–27. 2008. doi:10.1016/j.febslet.2008.05.012. PMID 18501714.
Further reading
- "Cellular localization and tissue expression pattern of UCA1, a non-coding RNA" (in Chinese). 南方医科大学学报 [Journal of Southern Medical University] 30 (1): 57–60. 2010. PMID 20117985. http://www.j-smu.com/pdf2/201001/20100157.pdf.
- "Gene expression profiling reveals upregulated UCA1 and BMF in gallbladder epithelia of children with pancreaticobiliary maljunction". Journal of Pediatric Gastroenterology and Nutrition 52 (6): 744–50. 2011. doi:10.1097/MPG.0b013e318214bd30. PMID 21593646.
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