Biology:Deacetylisoipecoside synthase

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deacetylisoipecoside synthase
Identifiers
EC number4.3.3.3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

The enzyme deacetylisoipecoside synthase (EC 4.3.3.3) catalyzes the chemical reaction

deacetylisoipecoside + H2O [math]\displaystyle{ \rightleftharpoons }[/math] dopamine + secologanin

This enzyme belongs to the family of lyases, specifically amine lyases, which cleave carbon-nitrogen bonds. The systematic name of this enzyme class is deacetylisoipecoside dopamine-lyase (secologanin-forming). It is also called deacetylisoipecoside dopamine-lyase. It participates in indole and ipecac alkaloid biosynthesis.

References

  • "Enzymatic condensation of dopamine and secologanin by cell-free extracts of Alangium lamarckii". Phytochemistry 45 (3): 477–484. 1997. doi:10.1016/S0031-9422(96)00828-X.