Biology:Hydroxylamine dehydrogenase
From HandWiki
| Hydroxylamine dehydrogenase | |||||||||
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| Identifiers | |||||||||
| EC number | 1.7.2.6 | ||||||||
| CAS number | 9075-43-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Hydroxylamine dehydrogenase (EC 1.7.2.6, HAO (ambiguous)) is an enzyme with systematic name hydroxylamine:ferricytochrome-c oxidoreductase.[1][2][3][4][5] This enzyme catalyses the following chemical reaction
- (1) hydroxylamine + H2O + 2 ferricytochrome c [math]\displaystyle{ \rightleftharpoons }[/math] nitrite + 2 ferrocytochrome c + 5 H+
- (2) hydroxylamine + ferricytochrome c [math]\displaystyle{ \rightleftharpoons }[/math] nitric oxide + ferrocytochrome c + 3 H+
The enzymes from the nitrifying bacterium Nitrosomonas europaea and the methylotrophic bacterium Methylococcus capsulatus are hemoproteins.
References
- ↑ "Studies of the hydroxylamine metabolism of Nitrosomonas europaea. I. Purification of hydroxylamine oxidase". Biochemistry 7 (1): 353–66. January 1968. doi:10.1021/bi00841a045. PMID 5758552.
- ↑ "Hydroxylamine oxidoreductase of Nitrosomonas. Production of nitric oxide from hydroxylamine". Biochimica et Biophysica Acta 571 (1): 12–20. November 1979. doi:10.1016/0005-2744(79)90220-1. PMID 497235.
- ↑ "Reaction of oxygen with hydroxylamine oxidoreductase of Nitrosomonas: fast kinetics". FEBS Letters 144 (2): 299–303. August 1982. doi:10.1016/0014-5793(82)80658-3. PMID 7117545.
- ↑ "Resolution of multiple heme centers of hydroxylamine oxidoreductase from Nitrosomonas. 1. Electron paramagnetic resonance spectroscopy". Biochemistry 21 (17): 3965–72. August 1982. doi:10.1021/bi00260a010. PMID 6289867.
- ↑ "Transcription of nitrification genes by the methane-oxidizing bacterium, Methylococcus capsulatus strain Bath". The ISME Journal 2 (12): 1213–20. December 2008. doi:10.1038/ismej.2008.71. PMID 18650926.
External links
- Hydroxylamine+dehydrogenase at the US National Library of Medicine Medical Subject Headings (MeSH)
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