Biology:Beta-apo-4'-carotenal oxygenase

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Beta-apo-4'-carotenal oxygenase
Identifiers
EC number1.2.1.82
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Beta-apo-4'-carotenal oxygenase (EC 1.2.1.82, beta-apo-4'-carotenal dehydrogenase, YLO-1, carD (gene)) is an enzyme with systematic name 4'-apo-beta,psi-carotenal:NAD+ oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction:

4'-apo-beta, psi-caroten-4'-al + NAD+ + H2O [math]\displaystyle{ \rightleftharpoons }[/math] neurosporaxanthin + NADH + 2 H+

Neurosporaxanthin is responsible for the orange color of Neurospora.

References

  1. "The ylo-1 gene encodes an aldehyde dehydrogenase responsible for the last reaction in the Neurospora carotenoid pathway". Molecular Microbiology 69 (5): 1207–20. September 2008. doi:10.1111/j.1365-2958.2008.06349.x. PMID 18627463. 
  2. "The gene carD encodes the aldehyde dehydrogenase responsible for neurosporaxanthin biosynthesis in Fusarium fujikuroi". The FEBS Journal 278 (17): 3164–76. September 2011. doi:10.1111/j.1742-4658.2011.08242.x. PMID 21749649. 

External links