Medicine:Ineffective erythropoiesis
From HandWiki
| Ineffective erythropoiesis | |
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| Specialty | Hematology |
Ineffective erythropoiesis is defined by the expansion of early-stage erythroid precursors driven by erythropoietin, accompanied by the apoptosis of late-stage precursors. This mechanism is principally responsible for the anemia seen in acquired conditions such as certain subtypes of myelodysplastic syndrome (MDS) and inherited disorders such as β-thalassemia, inherited sideroblastic anemias, as well as congenital dyserythropoietic anemias.[1]
See also
References
- ↑ Cazzola, Mario (21 April 2022). "Ineffective erythropoiesis and its treatment". Blood 139 (16): 2460–2470. doi:10.1182/blood.2021011045. ISSN 1528-0020. PMID 34932791. https://pubmed.ncbi.nlm.nih.gov/34932791/.
Further reading
- Ribeil, Jean-Antoine; Arlet, Jean-Benoit; Dussiot, Michael; Cruz Moura, Ivan; Courtois, Geneviève; Hermine, Olivier (28 March 2013). "Ineffective Erythropoiesis in β-Thalassemia". The Scientific World Journal 2013: e394295. doi:10.1155/2013/394295. ISSN 2356-6140. PMC 3628659. https://www.hindawi.com/journals/tswj/2013/394295/.
- Tanno, Toshihiko; Miller, Jeffery L. (11 May 2010). "Iron Loading and Overloading due to Ineffective Erythropoiesis". Advances in Hematology 2010: e358283. doi:10.1155/2010/358283. ISSN 1687-9104. https://www.hindawi.com/journals/ah/2010/358283/.
- Rivella, Stefano (2013). "Ineffective erythropoiesis and thalassemias". Current opinion in hematology 16 (3): 187–194. doi:10.1097/MOH.0b013e32832990a4. ISSN 1065-6251. PMID 19318943.
- Gupta, Ritama; Musallam, Khaled M.; Taher, Ali T.; Rivella, Stefano (2019). "Ineffective Erythropoiesis, Anemia and Iron Overload". Hematology/oncology clinics of North America 32 (2): 213–221. doi:10.1016/j.hoc.2017.11.009. ISSN 0889-8588. PMID 29458727.
External links
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