Medicine:Dennie–Marfan syndrome
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Revision as of 03:18, 30 December 2021 by imported>JTerm (fix)
| Dennie–Marfan syndrome | |
|---|---|
| Specialty | Neurology |
Dennie–Marfan syndrome is a syndrome in which there is association of spastic paraplegia of the lower limbs and mental retardation in children with congenital syphilis.[1] Both sexes are affected, and the onset of the disease can be acute or insidious, with slow progression from weakness to quadriplegia. Epilepsy, cataract, and nystagmus may also be found.[citation needed]
The syndrome was described by Charles Clayton Dennie in 1929,[2] and Antoine Marfan in 1936.[3]
References
- ↑ M.D, Mark E. Williams (2009) (in en). Geriatric Physical Diagnosis: A Guide to Observation and Assessment. McFarland. p. 56. ISBN 9780786451609.
- ↑ Dennie CC. Partial paralysis of the lower extremities in children, accompanied by backward mental development. Am J Syphilis 1929; 13: 157–163
- ↑ Marfan AB. Paraplégie spasmodique avec troubles cérébraux d’origine hérédo-syphilitique chez les grands enfants. Revue Franc Pédiat 1936; 12: 1–16
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