Chemistry:Zincophorin

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Zincophorin
Zincophorin.png
Names
Preferred IUPAC name
(2S)-2-{(2S,5S,6S)-5-Methyl-6-[(2S,3S,4S,5S,6S,7R,10E,12R,13R,14E,16R)-3,5,7,13-tetrahydroxy-4,6,12,14,16-pentamethylnonadeca-10,14-dien-2-yl]oxan-2-yl}propanoic acid
Other names
Griseochelin; Antibiotic M144255
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
Properties
C33H60O7
Molar mass 568.836 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Zincophorin (also known as griseochelin) is an antibiotic against Gram-positive bacteria and a bacterial metabolite.[1][2] It is also an ionophore.[3] It was isolated from the bacterium Streptomyces griseus.[4]

References

  1. GRÄFE, U.; SCHADE, W.; ROTH, M.; RADICS, L.; INCZE, M.; UJSZÁSZY, K. (1984). "Griseochelin, a novel carboxylic acid antibiotic from Streptomyces griseus". The Journal of Antibiotics 37 (8): 836–846. doi:10.7164/antibiotics.37.836. PMID 6434502. 
  2. Walther, E; Boldt, S; Kage, H; Lauterbach, T (November 28, 2016). "Zincophorin - biosynthesis in Streptomyces griseus and antibiotic properties". GMS Infectious Diseases 4: Doc08. doi:10.3205/id000026. PMID 30671322. 
  3. "griseochelin (CHEBI:141377)". https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:141377. 
  4. Walther, Elisabeth; Boldt, Sabrina; Kage, Hirokazu; Lauterbach, Tom; Martin, Karin; Roth, Martin; Hertweck, Christian; Sauerbrei, Andreas et al. (28 November 2016). "Zincophorin – biosynthesis in Streptomyces griseus and antibiotic properties". GMS Infectious Diseases 4: Doc08. doi:10.3205/id000026. PMID 30671322.