Biology:ENAH (gene)

Generic protein structure example

Protein enabled homolog is a protein that in humans is encoded by the ENAH gene.

Interactions

ENAH (gene) has been shown to interact with ABI1 and ZYX.

Further reading

• "A novel proline-rich motif present in ActA of Listeria monocytogenes and cytoskeletal proteins is the ligand for the EVH1 domain, a protein module present in the Ena/VASP family.". EMBO J. 16 (17): 5433–44. 1997. doi:10.1093/emboj/16.17.5433. PMID 9312002. 
• "The WW domain of neural protein FE65 interacts with proline-rich motifs in Mena, the mammalian homolog of Drosophila enabled.". J. Biol. Chem. 272 (52): 32869–77. 1998. doi:10.1074/jbc.272.52.32869. PMID 9407065. 
• "Interactions of drebrin and gephyrin with profilin.". Biochem. Biophys. Res. Commun. 243 (1): 86–9. 1998. doi:10.1006/bbrc.1997.8068. PMID 9473484. 
• "Accumulation of profilin II at the surface of Listeria is concomitant with the onset of motility and correlates with bacterial speed.". J. Cell Sci. 113 (8): 1415–26. 2000. PMID 10725224. 
• "Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton.". J. Cell Biol. 149 (1): 181–94. 2000. doi:10.1083/jcb.149.1.181. PMID 10747096. 
• "Characterization of the interaction between zyxin and members of the Ena/vasodilator-stimulated phosphoprotein family of proteins.". J. Biol. Chem. 275 (29): 22503–11. 2000. doi:10.1074/jbc.M001698200. PMID 10801818. 
• "Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex.". Curr. Biol. 11 (21): 1645–55. 2002. doi:10.1016/S0960-9822(01)00506-1. PMID 11696321. 
• "TES is a novel focal adhesion protein with a role in cell spreading.". J. Cell Sci. 116 (Pt 5): 897–906. 2003. doi:10.1242/jcs.00278. PMID 12571287. 
• "Abl interactor 1 promotes tyrosine 296 phosphorylation of mammalian enabled (Mena) by c-Abl kinase.". J. Biol. Chem. 278 (24): 21685–92. 2003. doi:10.1074/jbc.M301447200. PMID 12672821. 
• "The conformational state of Tes regulates its zyxin-dependent recruitment to focal adhesions.". J. Cell Biol. 161 (1): 33–9. 2003. doi:10.1083/jcb.200211015. PMID 12695497. 
• "Robo4 is a vascular-specific receptor that inhibits endothelial migration.". Dev. Biol. 261 (1): 251–67. 2003. doi:10.1016/S0012-1606(03)00258-6. PMID 12941633. 
• "Complex formation between the postsynaptic scaffolding protein gephyrin, profilin, and Mena: a possible link to the microfilament system.". J. Neurosci. 23 (23): 8330–9. 2003. doi:10.1523/JNEUROSCI.23-23-08330.2003. PMID 12967995. 
• "Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton.". J. Biol. Chem. 278 (49): 49031–43. 2004. doi:10.1074/jbc.M308104200. PMID 14506234. 
• "Exportin 6: a novel nuclear export receptor that is specific for profilin.actin complexes.". EMBO J. 22 (21): 5928–40. 2003. doi:10.1093/emboj/cdg565. PMID 14592989. 
• "Human Mena protein, a serex-defined antigen overexpressed in breast cancer eliciting both humoral and CD8+ T-cell immune response.". Int. J. Cancer 109 (6): 909–18. 2004. doi:10.1002/ijc.20094. PMID 15027125. 
• "Mammalian Fat1 cadherin regulates actin dynamics and cell-cell contact.". J. Cell Biol. 165 (4): 517–28. 2004. doi:10.1083/jcb.200403006. PMID 15148305. 
• "Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamics.". Dev. Cell 7 (4): 571–83. 2004. doi:10.1016/j.devcel.2004.07.024. PMID 15469845.