Biology:SPRED3
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Revision as of 15:53, 12 August 2022 by imported>Jworkorg (change)
 Generic protein structure example |
Sprouty-related, EVH1 domain-containing protein 3 also known as Spread-3 is a protein that in humans is encoded by the SPRED3 gene.[1]
Spread-3 is a member of the Sprouty (see SPRY1/SPRED) family of proteins that regulate growth factor-induced activation of the MAP kinase cascade.[1][2]
References
- ↑ 1.0 1.1 "Entrez Gene: sprouty-related". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=399473.
- ↑ "Spred-1 negatively regulates interleukin-3-mediated ERK/mitogen-activated protein (MAP) kinase activation in hematopoietic cells". The Journal of Biological Chemistry 279 (50): 52543–51. December 2004. doi:10.1074/jbc.M405189200. PMID 15465815.
Further reading
- "Molecular cloning of mammalian Spred-3 which suppresses tyrosine kinase-mediated Erk activation". Biochemical and Biophysical Research Communications 302 (4): 767–72. March 2003. doi:10.1016/S0006-291X(03)00259-6. PMID 12646235.
- "Mutation analysis of CBL-C and SPRED3 on 19q in human glioblastoma". Neurogenetics 5 (1): 81–2. February 2004. doi:10.1007/s10048-003-0164-x. PMID 14618415.
- "Eve-3: a liver enriched suppressor of Ras/MAPK signaling". Journal of Hepatology 44 (4): 758–67. April 2006. doi:10.1016/j.jhep.2005.10.031. PMID 16478641.
- "Spred-2 steady-state levels are regulated by phosphorylation and Cbl-mediated ubiquitination". Biochemical and Biophysical Research Communications 351 (4): 1018–23. December 2006. doi:10.1016/j.bbrc.2006.10.150. PMID 17094949.
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