Biography:Evelyn Telfer

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Evelyn Telfer is a reproductive biologist and professor at the University of Edinburgh. She leads a research team which has successfully grown the human eggs to maturity in the lab, and discovered that human ovaries are capable of growing new eggs. In 2018 she was named one of Porter magazine’s Incredible Women of 2018.

Education

Telfer obtained her PhD in 1987.[1] Her thesis investigated factors influencing the development of ovarian follicles in mammals.[2]

Career

Telfer is currently a reproductive biologist and Professor of Reproductive Biology at the University of Edinburgh.[3]

She is a former Associate Editor of Molecular Human Reproduction journal.[4]

From 1987-1989, Telfer worked in the Department of Physiology at the University of Edinburgh. Here, she worked with the physiologist Roger Gosden to develop a culture systems to support murine follicle development, one of the first of its kind.[1]

She led research which, in 2016, found evidence that the human ovary may have the capability to grow new eggs in adulthood. However, Telfer warned against premature clinical applications in fertility treatments before the findings have been fully understood.[5]

In 2018 she was named as one of Porter magazine’s Incredible Women of 2018, recognised for her research growing oocyte cells to maturity in the lab, to the point at which they can be fertilised.[6] The research was the first successful attempt to grow fully mature human eggs, where previously it had only been achieved for mouse eggs.[7] The technique has implications for fertility treatment, in particular in women undergoing in vitro fertilisation and women who had their ovaries removed before cancer treatment.[8] Telfer was the project leader,[9] and co-authored an article publishing the research in the medical journal Molecular Human Reproduction in March 2018.[3][10]

References

  1. 1.0 1.1 Telfer, Evelyn E; McLaughlin, Marie (2007). "Natural history of the mammalian oocyte" (in English). Reproductive BioMedicine Online 15 (3): 288–295. doi:10.1016/S1472-6483(10)60341-0. ISSN 1472-6483. https://www.rbmojournal.com/article/S1472-6483(10)60341-0/fulltext#Biography. 
  2. Elizabeth, Telfer, Evelyn (1988) (in en). Factors influencing follicular development in mammalian ovaries. https://www.era.lib.ed.ac.uk/handle/1842/26993. 
  3. 3.0 3.1 "These lab-grown human eggs could combat infertility—if they prove healthy" (in en). Science | AAAS. 2018-02-08. http://www.sciencemag.org/news/2018/02/these-lab-grown-human-eggs-could-combat-infertility-if-they-prove-healthy. 
  4. "Editorial_Board | MHR: Basic science of reproductive medicine | Oxford Academic" (in en). https://academic.oup.com/molehr/pages/Editorial_Board. 
  5. Devlin, Hannah (2016-10-07). "Evidence suggests women's ovaries can grow new eggs" (in en). http://www.theguardian.com/science/2016/oct/07/evidence-suggests-womens-ovaries-can-grow-new-eggs. 
  6. "Fertility pioneer receives international award" (in en). The University of Edinburgh. https://www.ed.ac.uk/news/2018/fertility-pioneer-receives-international-award. 
  7. Davis, Nicola (2018-02-09). "Breakthrough as human eggs developed in the lab for first time" (in en). http://www.theguardian.com/science/2018/feb/09/breakthrough-as-human-eggs-developed-in-the-lab-for-first-time. 
  8. Hamzelou, Jessica. "Primitive human eggs matured in the lab for the first time" (in en-US). New Scientist. https://www.newscientist.com/article/2160676-primitive-human-eggs-matured-in-the-lab-for-the-first-time/. 
  9. Cookson, Clive (9 February 2018). "Mature human eggs grown for first time by scientists in UK" (in en-GB). https://www.ft.com/content/70345084-0cc7-11e8-8eb7-42f857ea9f09. 
  10. McLaughlin, M; Albertini, D F; Wallace, W H B; Anderson, R A; Telfer, E E (2018-01-30). "Metaphase II oocytes from human unilaminar follicles grown in a multi-step culture system" (in en). MHR: Basic science of reproductive medicine 24 (3): 135–142. doi:10.1093/molehr/gay002. ISSN 1360-9947. https://doi.org/10.1093/molehr/gay002. 

External links