View source for Biology:DTDP-6-deoxy-L-talose 4-dehydrogenase (NAD+)

{{DISPLAYTITLE:dTDP-6-deoxy-L-talose 4-dehydrogenase (NAD<sup>+</sup>)}}
{{Infobox enzyme
| Name       = DTDP-6-deoxy-L-talose 4-dehydrogenase (NAD<sup>+</sup>)
| EC_number  = 1.1.1.339
| CAS_number =
| GO_code    = 
| image      = 
| width      = 
| caption    =  
}}
'''DTDP-6-deoxy-L-talose 4-dehydrogenase (NAD<sup>+</sup>)''' ({{EC number|1.1.1.339}}, ''tll (gene name)'') is an [[Biology:Enzyme|enzyme]] with [[Biology:List of enzymes|systematic name]] ''dTDP-6-deoxy-beta-L-talose:NAD<sup>+</sup> 4-oxidoreductase''.<ref>{{cite journal | vauthors = Nakano Y, Suzuki N, Yoshida Y, Nezu T, Yamashita Y, Koga T | title = Thymidine diphosphate-6-deoxy-L-lyxo-4-hexulose reductase synthesizing dTDP-6-deoxy-L-talose from Actinobacillus actinomycetemcomitans | journal = The Journal of Biological Chemistry | volume = 275 | issue = 10 | pages = 6806–12 | date = March 2000 | pmid = 10702238 | doi = 10.1074/jbc.275.10.6806 | doi-access = free }}</ref> This enzyme [[Chemistry:Catalysis|catalyses]] the following [[Chemistry:Chemical reaction|chemical reaction]]

: dTDP-6-deoxy-beta-L-talose + NAD<sup>+</sup> <math>\rightleftharpoons</math> dTDP-4-dehydro-6-deoxy-beta-L-mannose + NADH + H<sup>+</sup>

The enzyme from bacterium ''[[Biology:Aggregatibacter actinomycetemcomitans|Aggregatibacter actinomycetemcomitans]]'' participates in the biosynthesis of the serotype c-specific polysaccharide antigen.

== References ==
{{reflist}}

== External links ==
* {{MeshName|DTDP-6-deoxy-L-talose+4-dehydrogenase+(NAD+)}}

{{Alcohol oxidoreductases}}
{{Enzymes}}

[[Category:EC 1.1.1]]

{{Sourceattribution|DTDP-6-deoxy-L-talose 4-dehydrogenase (NAD+)}}