Biology:DTDP-6-deoxy-L-talose 4-dehydrogenase (NAD+)

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DTDP-6-deoxy-L-talose 4-dehydrogenase (NAD+)
Identifiers
EC number1.1.1.339
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

DTDP-6-deoxy-L-talose 4-dehydrogenase (NAD+) (EC 1.1.1.339, tll (gene name)) is an enzyme with systematic name dTDP-6-deoxy-beta-L-talose:NAD+ 4-oxidoreductase.[1] This enzyme catalyses the following chemical reaction

dTDP-6-deoxy-beta-L-talose + NAD+ [math]\displaystyle{ \rightleftharpoons }[/math] dTDP-4-dehydro-6-deoxy-beta-L-mannose + NADH + H+

The enzyme from bacterium Aggregatibacter actinomycetemcomitans participates in the biosynthesis of the serotype c-specific polysaccharide antigen.

References

  1. "Thymidine diphosphate-6-deoxy-L-lyxo-4-hexulose reductase synthesizing dTDP-6-deoxy-L-talose from Actinobacillus actinomycetemcomitans". The Journal of Biological Chemistry 275 (10): 6806–12. March 2000. doi:10.1074/jbc.275.10.6806. PMID 10702238. 

External links