Biology:GNAS-AS1
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Short description: Non-coding RNA in the species Homo sapiens
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In molecular biology, GNAS antisense RNA (non-protein coding), also known as GNAS-AS1, is a long non-coding RNA.It is antisense to the GNAS gene. It is an imprinted gene, expressed only from the paternal allele, suggesting that it may have a role in suppression of the paternal NESP55 allele encoded by GNAS.[1]
See also
- Long noncoding RNA
References
- ↑ "An imprinted antisense transcript at the human GNAS1 locus.". Hum Mol Genet 9 (5): 835–841. 2000. doi:10.1093/hmg/9.5.835. PMID 10749992.
Further reading
- "DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific.". Hum. Mol. Genet. 18 (21): 4046–4053. 2009. doi:10.1093/hmg/ddp353. PMID 19656776.
- "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. 2006. doi:10.1101/gr.4039406. PMID 16344560.
- "An imprinted antisense transcript at the human GNAS1 locus.". Hum. Mol. Genet. 9 (5): 835–841. 2000. doi:10.1093/hmg/9.5.835. PMID 10749992.
- "An imprinted transcript, antisense to Nesp, adds complexity to the cluster of imprinted genes at the mouse Gnas locus.". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3342–3346. 2000. doi:10.1073/pnas.050015397. PMID 10716699.
- "Tissue-specific expression of antisense and sense transcripts at the imprinted Gnas locus.". Genomics 69 (3): 295–304. 2000. doi:10.1006/geno.2000.6337. PMID 11056047.
- "Alternative non-coding splice variants of Nespas, an imprinted gene antisense to Nesp in the Gnas imprinting cluster.". Mamm. Genome 13 (2): 74–79. 2002. doi:10.1007/s00335-001-2102-2. PMID 11889554.
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