Chemistry:Threshold of toxilogical concern

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The threshold of toxilogical concern (or TTC) is a method for determining the level of exposure to chemicals above which would be considered toxic,[1] in cases where data about such chemicals is scarce or non-existent.[2][3][4][5][6]

References

  1. ↑ Kroes, R.; Kleiner, J.; Renwick, A. (August 2005). "The threshold of toxicological concern concept in risk assessment". Toxicological Sciences 86 (2): 226–230. doi:10.1093/toxsci/kfi169. ISSN 1096-6080. PMID 15829616. https://pubmed.ncbi.nlm.nih.gov/15829616/. 
  2. ↑ Abstract jhsph.edu
  3. ↑ Threshold of Toxicological Concern American Chemistry
  4. ↑ Serafimova, Rositsa; Coja, Tamara; Kass, George E. N. (2021). "Application of the Threshold of Toxicological Concern (TTC) in Food Safety: Challenges and Opportunities". Frontiers in Toxicology 3: 655951. doi:10.3389/ftox.2021.655951. ISSN 2673-3080. PMID 35295160. 
  5. ↑ Development, Office of Research &. "Derivation of New Threshold of Toxicological Concern Values for Exposure via Inhalation for Environmentally-Relevant Chemicals". https://cfpub.epa.gov/si/si_public_record_Report.cfm?dirEntryId=351559&Lab=CCTE. 
  6. ↑ Najjar, Abdulkarim; Ellison, Corie A.; Gregoire, Sebastien; Hewitt, Nicola J. (2023-01-01). "Practical application of the interim internal threshold of toxicological concern (iTTC): a case study based on clinical data" (in en). Archives of Toxicology 97 (1): 155–164. doi:10.1007/s00204-022-03371-6. ISSN 1432-0738. PMID 36149470. PMC 9816204. https://doi.org/10.1007/s00204-022-03371-6. 




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