Biography:Donald Engelman

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Donald Max Engelman
Websitemedicine.yale.edu/lab/engelman/
Born1941
EducationReed College, Yale University
AwardsGuggenheim fellow
Scientific career
FieldsCancer drugs and treatments
InstitutionsYale University
ThesisSolubilization and Aggregation Properties of Membrane Components from Mycoplasma laidlawii' (1968)
Doctoral studentsMark A. Lemmon[1][2]


Donald Max Engelman (born 1941) is Higgins Professor of Biochemistry at Yale University. He is a member of the National Academy of Sciences (1997), fellow of the American Academy of Arts and Sciences,[3] a fellow of the National Institutes of Health, and has been a Guggenheim fellow.[4] He served as the editor of the Annual Review of Biophysics and Biophysical Chemistry (1984–1993).[5]

He is a director of the Stryker Corporation.[6] He is involved in the creation of new cancer drugs and treatments.[7] For example, Engelman is involved in research to use peptides to aid in destroying tumors.[8]

Administration, advising, and consulting

Engelman has served as Director of Biological Sciences at Yale, an advisor to the Brookhaven National Laboratory, and a consultant to the Los Alamos National Laboratory.[9] He also served as Acting Dean of Yale College in 1991.[10]

Education

Engelman is a graduate (and trustee[11]) of Reed College receiving his degree in physics. He then earned his Ph.D. in molecular biophysics at Yale University in 1969.[12][13]

Engelman Lab

Engelman directs the Engelman Laboratory at Yale focused on the biophysics of biological membranes. His group is best known for elucidating the mechanism of pH Low Insertion Peptide (pHLIP) to form trans-membrane helices.[13][14]

Patents

Engelman holds six United States patents for his discoveries.[15]

References

  1. ↑ Lemmon, Mark A.; Flanagan, John M.; Treutlein, Herbert R.; Zhang, Jian; Engelman, Donald M. (1992). "Sequence specificity in the dimerization of transmembrane .alpha.-helixes". Biochemistry 31 (51): 12719–12725. doi:10.1021/bi00166a002. PMID 1463743. 
  2. ↑ Lemmon, Mark Andrew (1993). Specific interactions between transmembrane alpha-helices: Their role in the oligomerization of integral membrane proteins (PhD thesis). Yale University. ProQuest 304065037. (Subscription content?)
  3. ↑ "REED COLLEGE AMERICAN ACADEMY OF ARTS AND SCIENCES AWARDS". http://www.reed.edu/ir/aaa&swawards.html. 
  4. ↑ "All Fellows - John Simon Guggenheim Memorial Foundation". Gf.org. http://www.gf.org/fellows/all?index=e&page=5. 
  5. ↑ "Engelman and de la Huerga join the board of trustees". August 2000. https://www.reed.edu/reed_magazine/aug2000/b_news/5.html. 
  6. ↑ "Donald M. Engelman Profile - Forbes.com". People.forbes.com. https://people.forbes.com/profile/donald-m-engelman/75093. [|permanent dead link|dead link}}]
  7. ↑ redOrbit (27 October 2009). "URI Research Couple's Method Targets Cancerous Tumors - Redorbit". Redorbit. http://www.redorbit.com/news/health/1776007/uri_research_couples_method_targets_cancerous_tumors/. 
  8. ↑ "Home". http://www.healthimaging.com/index.php?option=com_articles&article=19339. 
  9. ↑ "Reed Magazine: News of the College". http://web.reed.edu/reed_magazine/aug2004/columns/NoC/engleman.html. 
  10. ↑ "A Yale College Dean Is Named". The New York Times. 1991-10-15. https://www.nytimes.com/1991/10/15/nyregion/a-yale-college-dean-is-named.html. 
  11. ↑ "List of Public Companies Worldwide, Letter - Businessweek - Businessweek". Businessweek.com. http://investing.businessweek.com/research/stocks/people/person.asp?personId=633961&ticker=SYK:US&previousCapId=3768366&previousTitle=Amherst%20College. [|permanent dead link|dead link}}]
  12. ↑ "The Engelman Lab - Donald M. Engelman". Yale.edu. http://www.yale.edu/engelman/DME.html. 
  13. ↑ 13.0 13.1 Roy, Yash; am, Giri Viswanathan 12:37 (2 February 2022). "Two Yale faculty members elected as fellows of the American Association for the Advancement of Science" (in en). Yale Daily News. https://yaledailynews.com/blog/2022/02/02/two-yale-faculty-members-elected-as-fellows-of-the-american-association-for-the-advancement-of-science/. 
  14. ↑ Reshetnyak, Yana K.; Andreev, Oleg A.; Segala, Michael; Markin, Vladislav S.; Engelman, Donald M. (7 October 2008). "Energetics of peptide (pHLIP) binding to and folding across a lipid bilayer membrane". Proceedings of the National Academy of Sciences 105 (40): 15340–15345. doi:10.1073/pnas.0804746105. PMID 18829441. Bibcode: 2008PNAS..10515340R. 
  15. ↑ "Donald M Engelman, Page 1". http://www.patentmaps.com/inventor/Donald_M_Engelman_1.html. 



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