Biography:Joan Oró

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Joan Oró
Joan Oró i Florensa
Born
Joan Oro

(1923-10-26)26 October 1923
Lleida, Spain
Died2 September 2004(2004-09-02) (aged 80)
Barcelona, Spain
EducationUniversity of Barcelona
Alma materBaylor College of Medicine
Known forResearch has been of importance in understanding the origin of life
AwardsOparin Medal
Scientific career
FieldsBiochemistry
InstitutionsNASA
Thesis (1956)

Joan Oró i Florensa, 1st Marquess of Oró (ca; 26 October 1923 – 2 September 2004) was a Spanish (Catalan) biochemist, whose research has been of importance in understanding the origin of life. Living in the United States for many years, he participated in several NASA missions, including the Apollo mission to the Moon and the Viking lander. He received the Oparin Medal for his contributions to the field of origins of life.

Early life and education

Joan Oró i Florensa was born on 26 October 1923, in Lleida, Catalonia, Spain, the youngest of five children.[1]

After completing secondary school late owing to the Spanish Civil War, he completed his undergraduate studies in chemistry, focusing on organic chemistry, at the University of Barcelona in 1947. He first tried to earn a living as a chemist, but that did not work, so he spent three years working at his father's bakery and saving money.[1]

After getting married and having children, he and his family moved to the United States in 1952, due to the scarce scientific resources offered by the Spanish academia at that time. He enrolled at the Rice Institute in Houston, Texas, and started doing graduate studies in chemical engineering. After working with Donald Rappoport, who was professor of biochemistry at Baylor College of Medicine, he switched to biochemistry, and in 1956 he obtained his PhD in biochemistry in Houston.[1]

Scientific and academic career

Oró became a full professor in University of Houston in 1963[1] where he founded and directed the department of biochemistry and biophysics. From the 1960s he worked with NASA on the Viking missions which explored the planet Mars.[2] His work was essential in the analysis of samples of Martian soil, questioning early suggestions that life might have been detected.[2]

Origins of life

One of his most important contributions was the prebiotic synthesis of the nucleobase adenine (a key component of nucleic acids) from hydrogen cyanide (HCN). He also showed that amino acids can be made from HCN plus ammonia in an aqueous solution.[3][4] This was achieved during the period 1959–1962 and stands, together with the Miller-Urey experiment, as one of the fundamental results of prebiotic chemistry. It opened up a research area eventually leading to the complete synthesis of other components of nucleic acids.

Cometary origin of prebiotic molecules

Oró was also the first scientist pointing towards comets as key carriers of organic molecules to our early biosphere. This conjecture (formulated in 1961)[5] is broadly accepted today. Although such an idea had been around for a long time, it was only when both space exploration and prebiotic chemistry fully developed that extensive evidence was in place. Comets are rich in carbon and water, bearing along precursor molecules based on carbon chemistry, such as amino acids. In this context, in 1971, Oró and co-workers published a paper revealing the high abundance of amino acids, aliphatic and aromatic hydrocarbons in the Murchison meteorite[6] and studied the optical activity of the amino acids.[7]

Viking mission

Oró also provided a chemical interpretation of a set of remarkable, and to some extent unexpected results reported by the Viking mission to Mars. The Viking lander performed a series of experiments, including one designed by Oró, involving a small gas chromatograph and mass spectrometer. In one of these experiments, where a set of nutrients was mixed with Martian soil samples, a sudden production of carbon dioxide was reported, initially suggesting the presence of Martian microbes, which would have shown some kind of metabolic processing of nutrients. Oró showed that a simpler, abiotic interpretation was more likely to be the correct one: the catalytic chemical oxidation of test nutrients.[2]

Other activities

Awards and honors

  • 1983: Cross of Civil Order of Alfonso X el Sabio (Madrid) *1986: Oparin Medal from the International Society for the Study of the Origin of Life (ISSOL) (Berkeley), *1991: Creu de Sant Jordi[8]
  • 2000: Medalla del President Francesc Macià *2003: Named "Marquess of Oró" in 2003 by Royal Decree 819-32003 of 23 June.[9]
  • 2024: Premio In Memoriam (Posthumous Award) in the Premios Vanguardia in Barcelona[10]

Personal life and death

Oró married Francesca Forteza in 1948, and they had four children, the first three born in Spain and the youngest born in Houston.[1]

Oró died in Barcelona on September 2, 2004.[11]

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Guerrero, Ricardo (March 2005). "Joan Oró: (1923-2004)". International Microbiology 8 (1): 63–68. PMID 15906264. http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1139-67092005000100010. 
  2. ↑ 2.0 2.1 2.2 Oró, Joan (1979). "Introduction". Journal of Molecular Evolution 14 (1–3): 3–4. doi:10.1007/BF01732362. Bibcode: 1979JMolE..14....3O. 
  3. ↑ Oró, J.; Kimball, A.P. (1961). "Synthesis of purines under possible primitive earth conditions. I. Adenine from hydrogen cyanide". Archives of Biochemistry and Biophysics 94 (2): 217–227. doi:10.1016/0003-9861(61)90033-9. PMID 13731263. 
  4. ↑ Oró, J. (1961). "Mechanism of Synthesis of Adenine from Hydrogen Cyanide under Possible Primitive Earth Conditions". Nature 191 (4794): 1193–1194. doi:10.1038/1911193a0. PMID 13731264. Bibcode: 1961Natur.191.1193O. 
  5. ↑ Oró, J. (1961). "Comets and the Formation of Biochemical Compounds on the Primitive Earth". Nature 190 (4774): 389–390. doi:10.1038/190389a0. Bibcode: 1961Natur.190..389O. 
  6. ↑ Oró, J.; Gibert, J.; Lichtenstein, H.; Wikstrom, S.; Flory, D. A. (1971). "Amino-acids, Aliphatic and Aromatic Hydrocarbons in the Murchison Meteorite". Nature 230 (5289): 105–106. doi:10.1038/230105a0. PMID 4927006. Bibcode: 1971Natur.230..105O. 
  7. ↑ Bada, Jeffrey L.; Cronin, John R.; Ho, Ming-Shan; Kvenvolden, Keith A.; Lawless, James G.; Miller, Stanley L.; Oro, J.; Steinberg, Spencer (1983). "On the reported optical activity of amino acids in the Murchison meteorite". Nature 301 (5900): 494–496. doi:10.1038/301494a0. Bibcode: 1983Natur.301..494B. 
  8. ↑ "DECRET 50/1991, de 4 de març, de concessió de les Creus de Sant Jordi de la Generalitat de Catalunya." (in ca-ES). http://portaljuridic.gencat.cat/ca/document-del-pjur/. 
  9. ↑ "BOE nº 150 de 24 de junio de 2003, R.D. nº 819/2003, de concesión del título de Marqués de Oró". http://www.boe.es/boe/dias/2003/06/24/pdfs/A24226-24226.pdf. 
  10. ↑ Abad, Martí (1 October 2024). "Premios Vanguardia 2024: la opositora rusa Yulia Naválnaya, premio Internacional" (in es). https://www.lavanguardia.com/vida/20240930/9984315/premios-vanguardia-2024-gala-premiados-en-directo.html. 
  11. ↑ "Mor als 80 anys el científic català Joan Oró" (in ca). 2004-09-03. https://www.ccma.cat/324/mor-als-80-anys-el-cientific-catala-joan-oro/noticia/73970/. 
Spanish nobility
New title Marquess of Oró
23 June 2003 – 2 September 2004 		Succeeded by
María Elena Oró Forteza



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