Biography:Karl Broman
Karl Broman is a professor at the University of Wisconsin–Madison (UWM) in the Biostatistics and Medical Informatics departments.[1] He has been employed at UWM since 2007 and previously was employed at Johns Hopkins University from 1999 - 2007.[1] Broman's original research focus was quantitative genetics,[2] although he has also become known for his work on reproducible research.[3] In 2016, Broman was named a Fellow of the American Statistical Association.
Research
Study of Bile Acids
In 2019 Karl Broman and a group of researchers published a study which found genetic variants in mice that impacted the bile acid levels in their guts.[4]
Broman's other highly-cited papers include:
- Broman, Karl W., et al. "Comprehensive human genetic maps: individual and sex-specific variation in recombination." The American Journal of Human Genetics 63.3 (1998): 861-869.
- Broman, Karl W., et al. "R/qtl: QTL mapping in experimental crosses." Bioinformatics 19.7 (2003): 889-890.
- Churchill, Gary A., et al. "The Collaborative Cross, a community resource for the genetic analysis of complex traits." Nature genetics 36.11 (2004): 1133.
Rstudio
Karl Broman created R (programming language) packages such as qtlcharts, QTL, and QTL2. These packages perform trait localization and visualizations of genetic data in high dimensions.[2]
References
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- ↑ 1.0 1.1 ORCID. "Karl W Broman (0000-0002-4914-6671)" (in en). https://orcid.org/0000-0002-4914-6671.
- ↑ 2.0 2.1 "Karl Broman" (in en-US). https://resources.rstudio.com/authors/karl-broman.
- ↑ "Get With the Program" (in en). https://www.the-scientist.com/lab-tools/get-with-the-program-35075.
- ↑ "Study of bile acids links individual's genetics and microbial gut community: Gene identified in mice affects both size of a bacterial population and bile acid levels in blood" (in en). https://www.sciencedaily.com/releases/2019/08/190829150828.htm.
