Biography:Lisa Jones (scientist)
Lisa Jones | |
|---|---|
| Alma mater | Syracuse University Georgia State University |
| Known for | Cell footprinting |
| Scientific career | |
| Institutions | University of Maryland Indiana University-Purdue University Indianapolis |
Lisa M. Jones is an Assistant Professor of Pharmaceutical Sciences at the University of Maryland, Baltimore.
Early life and education
Jones became interested in science as a freshman at high school, where she took part in a national Science Technology Engineering Program.[1] She went to college at Syracuse University, where she was the only person of colour.[2] Jones completed her PhD at Georgia State University and specialized in structural biology.[3]
Research and career
She was a Pfizer postdoctoral researcher at Washington University in St. Louis.[4][1] She joined Indiana University – Purdue University Indianapolis, where she became an Associate Professor.[5][6] In 2016 Jones won a $1.1 million National Science Foundation Career grant to develop new techniques to study cell membranes.[1] Her award supported research training for students from historically black colleges and universities to work in biochemistry.[1] She developed cell-footprinting, a technique that uses mass spectrometry coupled with in vivo fast photochemical oxidation of proteins (FPOP).[1][7][8] She is recognised as developing solving new questions in medicine as well as tools for biomedical researchers.[6]
She moved to the University of Maryland School of Pharmacy in 2016.[9] The Jones Lab is a structural proteomics group, who specialist in FPOP using an excimer laser for photolysis, which generates hydroxyl radicals.[10] Hydroxyl radicals go on to oxidise the side chains of amino acids and provide solvent accessibility of proteins within a cell.[11] FPOP can provide information on the sites of ligand binding, protein interaction and protein conformational changes.[10]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 "IUPUI chemist receives $1.1M NSF grant for research, training of minority future researchers: Newscenter: Indiana University–Purdue University Indianapolis". http://archive.news.iupui.edu/releases/2016/02/jones-nsf-career-award.shtml.
- ↑ @Victoria08Davis, VICTORIA T. DAVIS. "IUPUI chemist awarded more than $1 million for research, training of minority students" (in en). Indianapolis Recorder Newspaper. http://www.indianapolisrecorder.com/education/article_0ecb3e70-e168-11e5-93a7-2fe9d8bc44c2.html.
- ↑ Chea, Emily E.; Jones, Lisa M. (2018-02-12). "Analyzing the structure of macromolecules in their native cellular environment using hydroxyl radical footprinting" (in en). Analyst 143 (4). doi:10.1039/C7AN01323J. ISSN 1364-5528. http://pubs.rsc.org/-/content/articlelanding/2018/an/c7an01323j/unauth#!divAbstract.
- ↑ Jones, Lisa M.; Zhang, Hao; Vidavsky, Ilan; Gross, Michael L. (2010-02-15). "An On-Line, High-Pressure Digestion System for Protein Characterization by Hydrogen/Deuterium Exchange and Mass Spectrometry". Analytical Chemistry 82 (4): 1171–1174. doi:10.1021/ac902477u. PMID 20095571.
- ↑ "Lisa Jones" (in en). http://stem.indiana.edu/jones.html.
- ↑ 6.0 6.1 Brown, Alex. "IUPUI Professor Receives Lucrative Award" (in en). http://www.insideindianabusiness.com/story/31130059/iupui-professor-receives-prestigious-award.
- ↑ "NSF Award Search: Award#1701692 - CAREER: Development of an In Cell Footprinting Method for the Analysis of Protein Structure". https://www.nsf.gov/awardsearch/showAward?AWD_ID=1701692.
- ↑ Rinas, Aimee; Mali, Vishaal S.; Espino, Jessica A.; Jones, Lisa M. (2016-10-07). "Development of a Microflow System for In-Cell Footprinting Coupled with Mass Spectrometry" (in EN). Analytical Chemistry 88 (20): 10052–10058. doi:10.1021/acs.analchem.6b02357. http://pubs.acs.org/doi/10.1021/acs.analchem.6b02357.
- ↑ "Its official! We're getting FPOP in Baltimore!" (in en). http://proteomicsnews.blogspot.co.uk/2016/06/its-official-were-getting-fpop-in.html.
- ↑ 10.0 10.1 "Lisa Jones" (in en-US). http://faculty.rx.umaryland.edu/ljones/.
- ↑ "Professor Lisa Jones - Indiana University". 2014-09-24. http://www.utoledo.edu/nsm/chemistry/pdfs/Flyer%20for%20Dr%20Lisa%20Jones.pdf.
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