Biography:Nerea Irigoyen

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Short description: Virologist
Nerea Irigoyen

Born
Nerea Irigoyen Vergara

1981
NationalitySpanish
Alma mater
  • University of Navarra (BSc)
  • Autonomous University of Madrid (PhD)
Scientific career
FieldsVirology
Institutions
ThesisAnalysis of the assembly and maturation processes of the Infectious Bursal Disease Virus capsid (2009)
Doctoral advisorJosé Francisco Rodríguez Aguirre
Website{{{1}}}

Nerea Irigoyen Vergara (Zaragoza, Spain , 1981)[1][2] is a virologist specialized in Zika virus. She leads a research group at the Department of Pathology of Cambridge University, in the UK.[3][4]

Career and research

Nerea Irigoyen studied Pharmacy at the University of Navarra, Spain, and carried out her PhD at CNB-CSIC in Madrid, Spain, under the supervision of José Francisco Rodríguez and José Ruiz Castón.[5] During her predoctoral studies, she spent several months abroad in Trieste, Italy, and Cambridge, UK. After graduating, she moved to the University of Cambridge to work as a Sir Henry Wellcome postdoctoral researcher in Professor Ian Brierley's group in the Virology Division, where she also coordinated a project funded by the Medical Research Council.[6][7] In 2018, she established her own research group, to explore a new technique to explore cells infected by Zika, and other virus like coronavirus and retrovirus.[8] With the start of the COVID-19 pandemic, her group concentrated its efforts on the investigation of SARS-CoV-2, and developed novel pharmacological strategies against this type of infections.[9]

Nerea Irigoyen is one of the founding members of the Society of Spanish Researchers in the UK (SRUK/CERU),[7] an association that promotes communication between Spanish researchers living and working in the United Kingdom, as well as coordinates science communication and policy actions to bridge the gap with Spanish authorities and the general public.

Academic publications (selection)

  • Manipulation of the unfolded protein response: A pharmacological strategy against coronavirus infection. PLoS Pathogens, 2021.[10]
  • Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia. Nature, 2021.[11]
  • Hybrid gene origination creates human-virus chimeric proteins during infection. Cell, 2020.[12]
  • An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells. Nature Microbiology, 2019.[13]

References

  1. ↑ ArainfoNoticias (2021-12-30). "La Comunidad Aspasia ha recuperado y publicado en Wikipedia las biografías de 40 aragonesas" (in es). https://arainfo.org/la-comunidad-aspasia-ha-recuperado-y-publicado-en-wikipedia-las-biografias-de-40-aragonesas/. 
  2. ↑ Aragón, Heraldo de. "Nerea Irigoyen: "Si queremos que la próxima pandemia salga bien, hay que invertir en ciencia ya"" (in es). https://www.heraldo.es/noticias/aragon/2021/12/31/nerea-irigoyen-si-queremos-que-la-proxima-pandemia-salga-bien-hay-que-invertir-en-ciencia-ya-1541852.html. 
  3. ↑ Irigoyen, Dr Nerea (2019-04-26). "Dr Nerea Irigoyen" (in en). https://www.path.cam.ac.uk/directory/dr-nerea-irigoyen. 
  4. ↑ Irigoyen, Nerea; Dinan, Adam M.; Meredith, Luke W.; Goodfellow, Ian; Brierley, Ian; Firth, Andrew E. (2017-03-02) (in en). The translational landscape of Zika virus during infection of mammalian and insect cells. pp. 112904. doi:10.1101/112904. https://www.biorxiv.org/content/10.1101/112904v1. 
  5. ↑ "Nerea Irigoyen Vergara" (in en-GB). https://sruk.org.uk/team/nerea-irigoyen-vergara/. 
  6. ↑ "Ribosomal frame-shifting and read-through in virus gene expression" (in en). https://wellcome.org/grant-funding/people-and-projects/grants-awarded/ribosomal-frameshifting-readthrough-virus-gene-expression. 
  7. ↑ 7.0 7.1 "The academic career and other science jobs the United Kingdom". 27 November 2015. https://www.fundacionareces.es/recursos/doc/portal/2018/04/20/5-nerea-irigoyen-vergara-en.pdf. 
  8. ↑ "Spotlight on... Nerea Irigoyen" (in en). https://express.adobe.com/page/XgIedKjzqxUaz/. 
  9. ↑ Echavarría-Consuegra, Liliana; Cook, Georgia M.; Busnadiego, Idoia; Lefèvre, Charlotte; Keep, Sarah; Brown, Katherine; Doyle, Nicole; Dowgier, Giulia et al. (2021-06-17). "Manipulation of the unfolded protein response: A pharmacological strategy against coronavirus infection" (in en). PLOS Pathogens 17 (6): e1009644. doi:10.1371/journal.ppat.1009644. ISSN 1553-7374. PMID 34138976. 
  10. ↑ Echavarría-Consuegra, Liliana; Cook, Georgia M.; Busnadiego, Idoia; Lefèvre, Charlotte; Keep, Sarah; Brown, Katherine; Doyle, Nicole; Dowgier, Giulia et al. (2021-06-17). Lee, Benhur. ed. "Manipulation of the unfolded protein response: A pharmacological strategy against coronavirus infection" (in en). PLOS Pathogens 17 (6): e1009644. doi:10.1371/journal.ppat.1009644. ISSN 1553-7374. PMID 34138976. 
  11. ↑ Yankova, Eliza; Blackaby, Wesley; Albertella, Mark; Rak, Justyna; De Braekeleer, Etienne; Tsagkogeorga, Georgia; Pilka, Ewa S.; Aspris, Demetrios et al. (2021-04-26). "Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia" (in en). Nature 593 (7860): 597–601. doi:10.1038/s41586-021-03536-w. ISSN 1476-4687. PMID 33902106. Bibcode: 2021Natur.593..597Y. 
  12. ↑ Ho, Jessica Sook Yuin; Angel, Matthew; Ma, Yixuan; Sloan, Elizabeth; Wang, Guojun; Martinez-Romero, Carles; Alenquer, Marta; Roudko, Vladimir et al. (2020-06-25). "Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection" (in en). Cell 181 (7): 1502–1517.e23. doi:10.1016/j.cell.2020.05.035. ISSN 0092-8674. PMID 32559462. 
  13. ↑ Lulla, Valeria; Dinan, Adam M.; Hosmillo, Myra; Chaudhry, Yasmin; Sherry, Lee; Irigoyen, Nerea; Nayak, Komal M.; Stonehouse, Nicola J. et al. (2019). "An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells" (in en). Nature Microbiology 4 (2): 280–292. doi:10.1038/s41564-018-0297-1. ISSN 2058-5276. PMID 30478287. 

External links



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