Biography:Roxana Moslehi

Short description: Genetic epidemiologist

Roxana Moslehi
Moslehi at the east campus of the University at Albany
Born	Iran
Academic background
Alma mater	University of British Columbia (BSc, MSc, PhD)
Academic advisors	J. M. Friedman Steven Narod
Academic work
Discipline	Epidemiologist
Sub-discipline	Genetic epidemiology
Institutions	University of Albany

Roxana Moslehi (Persian: رکسانا مصلحی‎) is an Iranian-born genetic epidemiologist.

Most of her research is on cancer and cancer precursors, including work on radiation-induced cancer of the eyes, genetic and environmental causes of ovarian cancer, and ethnic differences in breast cancer incidence. She also conducts molecular epidemiologic and genomic studies of other diseases such as myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS) and gestational complications. She is currently an associate professor in Epidemiology and Biostatistics in the School of Public Health at the University at Albany in New York State, where she has been teaching multiple courses, including those she developed in genetic and molecular epidemiology.

Education

Moslehi received her B.Sc. with honors, M.Sc. and Ph.D. degrees from the University of British Columbia (UBC) in Vancouver , Canada. Following her Ph.D. under the mentorship of Drs. J.M. Friedman and Steven Narod, she completed a postdoctoral fellowship at the National Institutes of Health (NIH), Division of Cancer Epidemiology and Genetics (DCEG) under the supervision of Mitchell Gail. While a postdoctoral fellow at the NIH, she received an adjunct assistant professor position at George Washington University (GWU), where she co-taught a course entitled "controversies in cancer epidemiology".

Selected publications

1. Moslehi, R.; Kariminejad, M. H.; Ghafari, V.; Narod, S. (2003). "Analysis of BRCA1 and BRCA2 mutations in an Iranian family with hereditary breast and ovarian cancer syndrome". American Journal of Medical Genetics. Part A 117A (3): 304–305. doi:10.1002/ajmg.a.10031. PMID 12599199. https://zenodo.org/record/1229105. 
2. Cass, I.; Baldwin, R. L.; Varkey, T.; Moslehi, R.; Narod, S. A.; Karlan, B. Y. (2003). "Improved survival in women with BRCA-associated ovarian carcinoma". Cancer 97 (9): 2187–2195. doi:10.1002/cncr.11310. PMID 12712470. 
3. Modugno, F.; Moslehi, R.; Ness, R. B.; Nelson, D. B.; Belle, S.; Kant, J. A.; Wheeler, J. E.; Wonderlick, A. et al. (2003). "Reproductive factors and ovarian cancer risk in Jewish BRCA1 and BRCA2 mutation carriers (United States)". Cancer Causes & Control 14 (5): 439–446. doi:10.1023/a:1024932427503. PMID 12946038. 
4. Goldin, L. R.; Camp, N. J.; Keen, K. J.; Martin, L. J.; Moslehi, R.; Ghosh, S.; North, K. E.; Wyszynski, D. F. et al. (2003). "Analysis of metabolic syndrome phenotypes in Framingham Heart Study families from Genetic Analysis Workshop 13". Genetic Epidemiology 25 (Suppl 1): S78-89. doi:10.1002/gepi.10288. PMID 14635173. 
5. Moslehi, R.; Goldstein, A. M.; Beerman, M.; Goldin, L.; Bergen, A. W.; Framingham Heart, Study (2003). "A genome-wide linkage scan for body mass index on Framingham Heart Study families". BMC Genetics 4 (Suppl 1): S97. doi:10.1186/1471-2156-4-S1-S97. PMID 14975165. 
6. Moslehi, R.; Devesa, S. S.; Schairer, C.; Fraumeni Jr, J. F. (2006). "Rapidly increasing incidence of ocular non-hodgkin lymphoma". Journal of the National Cancer Institute 98 (13): 936–939. doi:10.1093/jnci/djj248. PMID 16818858. 
7. Moslehi, R.; Chatterjee, N.; Church, T. R.; Chen, J.; Yeager, M.; Weissfeld, J.; Hein, D. W.; Hayes, R. B. (2006). "Cigarette smoking, N-acetyltransferase genes and the risk of advanced colorectal adenoma". Pharmacogenomics 7 (6): 819–829. doi:10.2217/14622416.7.6.819. PMID 16981843. https://zenodo.org/record/1236431. 
8. Zhang, L.; Gail, M. H.; Wang, Y. Q.; Brown, L. M.; Pan, K. F.; Ma, J. L.; Amagase, H.; You, W. C. et al. (2006). "A randomized factorial study of the effects of long-term garlic and micronutrient supplementation and of 2-wk antibiotic treatment for Helicobacter pylori infection on serum cholesterol and lipoproteins". The American Journal of Clinical Nutrition 84 (4): 912–919. doi:10.1093/ajcn/84.4.912. PMID 17023720. 
9. Chatterjee, N.; Kalaylioglu, Z.; Moslehi, R.; Peters, U.; Wacholder, S. (2006). "Powerful multilocus tests of genetic association in the presence of gene-gene and gene-environment interactions". American Journal of Human Genetics 79 (6): 1002–1016. doi:10.1086/509704. PMID 17186459. 
10. Ahn, J.; Moslehi, R.; Weinstein, S. J.; Snyder, K.; Virtamo, J.; Albanes, D. (2008). "Family history of prostate cancer and prostate cancer risk in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study". International Journal of Cancer 123 (5): 1154–1159. doi:10.1002/ijc.23591. PMID 18546266. 
11. Wang, Y.; Zhang, L.; Moslehi, R.; Ma, J.; Pan, K.; Zhou, T.; Liu, W.; Brown, L. M. et al. (2009). "Long-term garlic or micronutrient supplementation, but not anti-Helicobacter pylori therapy, increases serum folate or glutathione without affecting serum vitamin B-12 or homocysteine in a rural Chinese population". The Journal of Nutrition 139 (1): 106–112. doi:10.3945/jn.108.091389. PMID 19056661. 
12. Kuznetsov, I. B.; McDuffie, M.; Moslehi, R. (2009). "A web server for inferring the human N-acetyltransferase-2 (NAT2) enzymatic phenotype from NAT2 genotype". Bioinformatics 25 (9): 1185–1186. doi:10.1093/bioinformatics/btp121. PMID 19261719. 
13. Tan, X. L.; Moslehi, R.; Han, W.; Spivack, S. D. (2009). "Haplotype-tagging single nucleotide polymorphisms in the GSTP1 gene promoter and susceptibility to lung cancer". Cancer Detection and Prevention 32 (5–6): 403–415. doi:10.1016/j.cdp.2009.02.004. PMID 19282111. 
14. Moslehi, R.; Singh, R.; Lessner, L.; Friedman, J. M. (2010). "Impact of BRCA mutations on female fertility and offspring sex ratio". American Journal of Human Biology 22 (2): 201–205. doi:10.1002/ajhb.20978. PMID 19642207. 
15. Tamura, D.; Merideth, M.; Digiovanna, J. J.; Zhou, X.; Tucker, M. A.; Goldstein, A. M.; Brooks, B. P.; Khan, S. G. et al. (2011). "High-risk pregnancy and neonatal complications in the DNA repair and transcription disorder trichothiodystrophy: Report of 27 affected pregnancies". Prenatal Diagnosis 31 (11): 1046–1053. doi:10.1002/pd.2829. PMID 21800331. 
16. Moslehi, R.; Kumar, A.; Mills, J. L.; Ambroggio, X.; Signore, C.; Dzutsev, A. (2012). "Phenotype-specific adverse effects of XPD mutations on human prenatal development implicate impairment of TFIIH-mediated functions in placenta". European Journal of Human Genetics 20 (6): 626–631. doi:10.1038/ejhg.2011.249. PMID 22234153. 
17. Chen, L.; Bell, E. M.; Browne, M. L.; Druschel, C. M.; Romitti, P. A.; Schmidt, R. J.; Burns, T. L.; Moslehi, R. et al. (2012). "Maternal caffeine consumption and risk of congenital limb deficiencies". Birth Defects Research. Part A, Clinical and Molecular Teratology 94 (12): 1033–1043. doi:10.1002/bdra.23050. PMID 22903936. 
18. Zeinomar, N.; Moslehi, R. (2013). "The effectiveness of a community-based breast cancer education intervention in the New York State Capital Region". Journal of Cancer Education 28 (3): 466–473. doi:10.1007/s13187-013-0488-7. PMID 23749424. 
19. Moslehi, R.; Schymura, M. J.; Nayak, S.; Coles, F. B. (2011). "Ocular adnexal non-Hodgkin's lymphoma: A review of epidemiology and risk factors". Expert Review of Ophthalmology 6 (2): 181–193. doi:10.1586/eop.11.15. PMID 23976898. 
20. Moslehi, R.; Mills, J. L.; Signore, C.; Kumar, A.; Ambroggio, X.; Dzutsev, A. (2013). "Integrative transcriptome analysis reveals dysregulation of canonical cancer molecular pathways in placenta leading to preeclampsia". Scientific Reports 3: 2407. doi:10.1038/srep02407. PMID 23989136. Bibcode: 2013NatSR...3E2407M. 
21. Moslehi, R.; Coles, F. B.; Schymura, M. J. (2011). "Descriptive epidemiology of ophthalmic and ocular adnexal non-Hodgkin's lymphoma". Expert Review of Ophthalmology 6 (2): 175–180. doi:10.1586/eop.11.16. PMID 24353742. 
22. Moslehi, R.; Ambroggio, X.; Nagarajan, V.; Kumar, A.; Dzutsev, A. (2014). "Nucleotide excision repair/Transcription gene defects in the fetus and impaired TFIIH-mediated function in transcription in placenta leading to preeclampsia". BMC Genomics 15: 373. doi:10.1186/1471-2164-15-373. PMID 24885447. 
23. Moslehi, R.; Freedman, E.; Zeinomar, N.; Veneroso, C.; Levine, P. H. (2016). "Importance of hereditary and selected environmental risk factors in the etiology of inflammatory breast cancer: A case-comparison study". BMC Cancer 16: 334. doi:10.1186/s12885-016-2369-z. PMID 27229687. 
24. Kempin, S.; Finger, P. T.; Gale, R. P.; Rescigno, J.; Rubin, J.; Choi, W.; Fisher, R.; Aizman, A. et al. (2018). "A cluster of vitreoretinal lymphoma in New York with possible link to the Chernobyl nuclear disaster". Leukemia & Lymphoma 59 (8): 1998–2001. doi:10.1080/10428194.2017.1403025. PMID 29164983. 
25. Moslehi, R.; Zeinomar, N.; Boscoe, F. P. (2018). "Incidence of cutaneous malignant melanoma in Iranian provinces and American states matched on ultraviolet radiation exposure: An ecologic study". Environmental Pollution 234: 699–706. doi:10.1016/j.envpol.2017.11.099. PMID 29241156. 
26. Moslehi, R.; Tsao, H. S.; Zeinomar, N.; Stagnar, C.; Fitzpatrick, S.; Dzutsev, A. (2020). "Integrative genomic analysis implicates ERCC6 and its interaction with ERCC8 in susceptibility to breast cancer". Scientific Reports 10 (1): 21276. doi:10.1038/s41598-020-77037-7. PMID 33277540. Bibcode: 2020NatSR..1021276M. 
27. Moslehi, R.; Stagnar, C.; Srinivasan, S.; Radziszowski, P.; Carpenter, D. O. (2021). "The possible role of arsenic and gene-arsenic interactions in susceptibility to breast cancer: A systematic review". Reviews on Environmental Health 36 (4): 523–534. doi:10.1515/reveh-2020-0080. PMID 34223716. 
28. Maloney, B.; Park, S.; Sowizral, M.; Brackett, I.; Moslehi, R.; Chung, W. K.; Gruber, D.; Brower, A. et al. (2023). "Factors influencing creatine kinase-MM concentrations in newborns and implications for newborn screening for Duchenne muscular dystrophy". Clinical Biochemistry 118. doi:10.1016/j.clinbiochem.2023.110614. PMID 37479106.