Biography:Russell A. Brown

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Short description: American physician and computer scientist
Russell A. Brown in 2007

Russell A. Brown, an American physician and computer scientist, is the inventor[1] of the N-localizer[2] technology that enables guidance of stereotactic surgery or radiosurgery using medical images that are obtained via computed tomography (CT),[3] magnetic resonance imaging (MRI),[4] or positron emission tomography (PET).[5]

Brown invented the N-localizer in 1978 when he was a medical student [6] investigating image-guided surgery in the laboratory of his mentor, James A. Nelson, at the University of Utah. A few months later, Brown designed and built the first CT-compatible stereotactic frame in order to test the concept of the N-localizer.[7]

Brown also made contributions to the k-d tree[8] and to the generalized Born model[9] of implicit solvation.

References

  1. "System Using Computed Tomography as for Selective Body Treatment". U.S. Patent 4608977. 1986. 
  2. Galloway, RL Jr. (2015). "Introduction and Historical Perspectives on Image-Guided Surgery". in Golby, AJ. Image-Guided Neurosurgery. Amsterdam: Elsevier. pp. 3–4. 
  3. "CT-guided stereotactic neurosurgery: experience in 24 cases with a new stereotactic system". Journal of Neurology, Neurosurgery & Psychiatry 47 (1): 9–16. 1984. doi:10.1136/jnnp.47.1.9. PMID 6363629. 
  4. "Brown-Roberts-Wells stereotactic frame modifications to accomplish magnetic resonance imaging guidance in three planes". Applied Neurophysiology 50 (1–6): 143–152. 1987. doi:10.1159/000100700. PMID 3329837. 
  5. "Positron emission tomography imaging-directed stereotactic neurosurgery". Stereotactic and Functional Neurosurgery 58 (1–4): 134–140. 1992. doi:10.1159/000098986. PMID 1439330. 
  6. Gildenberg, PL; Krauss, JK (2009). "History of Stereotactic Surgery". in Lozano, AM; Gildenberg, PL; Tasker, RR. Textbook of Stereotactic and Functional Neurosurgery. Berlin: Springer-Verlag. pp. 23. 
  7. Inventing the N-Localizer for Stereotactic Neurosurgery: the Story of a Young Researcher in Radiology and Imaging Sciences.. 2017. https://medicine.utah.edu/radiology/news/2017/08/russ-brown-n-localizer.php. 
  8. Brown R (2015). "Building a balanced k-d tree in O(kn log n) time". Journal of Computer Graphics Techniques 4 (1): 50–68. http://jcgt.org/published/0004/01/03/. 
  9. "Second derivatives in generalized Born theory". Journal of Computational Chemistry 27 (14): 1662–1675. 2006. doi:10.1002/jcc.20479. PMID 16900491.