Biography:William K. Oh

Short description: American cancer researcher

William K. Oh, M.D.
Education	Yale University, NYU
Medical career
Profession	medical oncologist
Institutions	Harvard Medical School Mount Sinai Medical Center
Sub-specialties	genitourinary oncology
Research	cancer research

William K. Oh, is an American medical oncologist, academic and industry leader and expert in the management of genitourinary malignancies, including prostate, renal, bladder and testicular cancers.

Oh is Chief Medical Officer for the Prostate Cancer Foundation, the world’s leading philanthropy for prostate cancer. He previously served as CMO for Sema4, a publicly traded genomics and health intelligence company. For 11 years, Oh was Chief of the Division of Hematology and Medical Oncology at The Mount Sinai Medical Center in New York City , Deputy Director at Mount Sinai's NCI-designated Tisch Cancer Institute, Professor of Medicine and Urology and the Ezra M. Greenspan, M.D., Professor in Clinical Cancer Therapeutics at The Icahn School of Medicine at Mount Sinai.

Oh is the author of more than 350 articles and 125 abstracts. He is the editor of 6 books and the author of 25 book chapters. He has been listed in Castle Connolly's "America's Top Doctors for Cancer" from 2008 to 2022, "Best Doctors in America" from 2003 to 2022, was listed among New York Magazine's "Top Doctors" from 2010–2022. He continues on the faculty at Mount Sinai as Clinical Professor of Medicine in the Tisch Cancer Institute.

Biography

Oh was born in South Korea and immigrated to the US as a child. He earned a B.S. from Yale University in 1987 and his M.D. from New York University School of Medicine in 1992. He completed an internship and a residency at Brigham and Women's Hospital in Boston and a clinical fellowship at the Dana–Farber Cancer Institute.

From 1997 to 2009, Oh served on the faculty of Harvard Medical School, where he was Associate Professor of Medicine and Clinical Director of the Lank Center for Genitourinary Oncology. In 2009, he joined The Mount Sinai Medical Center as the Ezra M. Greenspan Professor in Clinical Cancer Therapeutics and Professor of Medicine and Urology, as well as Chief of the Division of Hematology and Medical Oncology in Mount Sinai's Department of Medicine.

Oh is a leading member of the American Society of Clinical Oncology. He has served on multiple editorial boards including the journals The Prostate, Clinical Genitourinary Cancer, the American Journal of Hematology and Oncology and CA – A Cancer Journal for Clinicians.

He co-edited the book Mount Sinai Expert Guides: Oncology which was published in 2019.

Oh has been the principal investigator on multiple clinical trials of chemotherapy in castration-resistant (CRPC) prostate cancer and for three trials of neoadjuvant chemotherapy in high-risk localized prostate cancer patients.

At the Dana–Farber Cancer Institute, from 2000 to 2009, Oh developed and managed a prospective clinical database linked to blood and tissue banks for more than 8,000 prostate cancer patients, with links to blood samples and tissue repositories, for exploration of research and prognostic applications, including: efficacy of various therapies in CRPC, hormonal therapy, testosterone as a marker for cancer outcome, relapse predictions based on nutritional factors at diagnosis and autoantibody signatures, and assessment of pharmacogenomic patterns predicting Gleason score. At Mount Sinai, he continued this work and developed a clinicogenomic database that resulted in multiple publications.

Honors and awards

• 1992 Alpha Omega Alpha
• 1992 Prize in Internal Medicine, NYU School of Medicine
• 1997 ASCO/AACR Methods in Clinical Cancer Research Workshop
• 2003 Compassionate Caregiver of the Year, Kenneth B. Schwartz Center, Honorable Mention
• 2003–present, Best Doctors in America
• 2005 2009 Boston Magazine "Top Doctors"
• 2007–2008 Brigham/Harvard Business School Physician Leadership Program
• 2008–present, America's Top Doctors for Cancer (Castle Connolly)
• 2010 Prostate Cancer Foundation Creativity Award
• 2010–present, New York Magazine "Top Doctors"
• 2011 Election to the American Society of Clinical Investigation (ASCI)
• 2013 Fellow, American College of Physicians (FACP)

Publications

Partial list:

• "Hormone-refractory prostate cancer: current standards and future prospects". J Urol 160 (4): 1220-29. October 1998. PMID 9751323. 
• "A phase II study of estramustine, docetaxel, and carboplatin with granulocyte-colony-stimulating factor support in patients with hormone-refractory prostate carcinoma: Cancer and Leukemia Group B 99813". Cancer 98 (12): 2592–8. December 2003. doi:10.1002/cncr.11829. PMID 14669278. 
• "Neoadjuvant docetaxel before radical prostatectomy in patients with high-risk localized prostate cancer". Clin. Cancer Res. 11 (14): 5233–40. July 2005. doi:10.1158/1078-0432.CCR-05-0299. PMID 16033841. 
• "Development of an integrated prostate cancer research information system". Clin Genitourin Cancer 5 (1): 61–6. June 2006. doi:10.3816/CGC.2006.n.019. PMID 16859581. 
• "Does oral antiandrogen use before leuteinizing hormone-releasing hormone therapy in patients with metastatic prostate cancer prevent clinical consequences of a testosterone flare?". Urology 75 (3): 642–7. March 2010. doi:10.1016/j.urology.2009.08.008. PMID 19962733. 
• "Inherited variation in the androgen pathway is associated with the efficacy of androgen-deprivation therapy in men with prostate cancer". J. Clin. Oncol. 26 (6): 842–7. February 2008. doi:10.1200/JCO.2007.13.6804. PMID 18281655. 
• "A whole-blood RNA transcript-based prognostic model in men with castration-resistant prostate cancer: a prospective study". Lancet Oncol. 13 (11): 1105-13. November 2012. doi:10.1016/S1470-2045(12)70263-2. PMID 23059047. 
• ""Does Circulating Tumor DNA Measure Up to Prostate-Specific Antigen?"". JAMA Oncol. 8 (7): 972-974. July 2022. doi:10.1001/jamaoncol.2022.0511. PMID 35551363. 
• ""Management of de novo metastatic hormone-sensitive prostate cancer: A comprehensive report of a single-center experience."". PLoS One 17 (8): e0264800. August 2022. doi:10.1371/journal.pone.0264800. PMID 35984843. 

External links

• Mount Sinai Hospital homepage
• Icahn School of Medicine at Mount Sinai homepage
• Prostate Cancer Foundation homepage