Biography:Yi Tang (biochemist)
Yi Tang is a biochemist and professor in the Department of Chemistry and Biochemistry and the Department of Chemical and Biomolecular Engineering at the University of California, Los Angeles.[1][2] His research interests include the discovery, functional characterization, and engineering of natural product biosynthetic enzymes.[3] He was awarded the 2014 Eli Lilly Award in Biological Chemistry.[4]
Education
Tang attended college at Pennsylvania State University and earned his PhD in Chemistry in 2002 from the California Institute of Technology, where he worked in the lab of Professor David Tirrell.[5]
Career and research
From 2002 to 2004, Tang pursued postdoctoral studies at the Stanford University in the lab of Professor Chaitan Khosla. In 2004, Tang joined the faculty of the Department of Chemical and Biomolecular Engineering the University of California, Los Angeles. His group's research has focused on studying the biosynthesis of natural products from Streptomyces and filamentous fungi as well as engineering enzymes that can be used for the production of pharmaceutical compounds. One demonstration of the latter approach has been his group's development of a biocatalytic approach for making the commonly prescribed lipid-lowering medication simvastatin.[6][7]
Web of Science lists 254 publications authored by Tang in peer-reviewed scientific journals that have been cited over 10,000 times, leading to an h-index of 58.[8] His lab's three most cited papers have been cited >180 times each.[9][10][11]
Awards and honors
- 2006 – National Science Foundation Career Award
- 2006 – Presidential Early Career Award in Science and Engineering (PECASE)
- 2008 – The Camille Dreyfus Teacher Scholar Award
- 2009 – Sloan Research Fellowship
- 2010 – Society for Industrial Microbiology (SIM) Young Investigator Award
- 2012 – American Chemical Society Arthur C. Cope Scholar Award
- 2012 – National Institute of Health Director’s Pioneer Award (DP1)
- 2014 – Eli Lilly Award in Biological Chemistry
- 2015 – California Institute of Technology Chemical Engineering Robert W. Vaughan Lectureship
References
- ↑ 1.0 1.1 "Yi Tang Lab@UCLA - Members" (in en-US). https://sites.google.com/site/yitanglab/members.
- ↑ 2.0 2.1 "Tang, Yi" (in en-US). https://www.packard.org/what-we-fund/science/packard-fellowships-for-science-and-engineering/fellowship-directory/tang-yi/.
- ↑ "Yi Tang". https://scholar.google.com/citations?user=dhq0ZK0AAAAJ&hl=en.
- ↑ ACS Division of Biological Chemistry (7 January 2023). "Previous Eli Lilly Award in Biological Chemistry Recipients". http://oldsite.divbiolchem.org/content/lillyawardees1.pdf.
- ↑ "Fluorinated Coiled-Coil Proteins Prepared In Vivo Display Enhanced Thermal and Chemical Stability". Angewandte Chemie 40 (8): 1494–1496. April 2001. doi:10.1002/1521-3773(20010417)40:8<1494::AID-ANIE1494>3.0.CO;2-X. PMID 29712367.
- ↑ "Structural secrets of enzyme used to make popular anti-cholesterol drug revealed" (in en). https://www.sciencedaily.com/releases/2014/05/140513152957.htm.
- ↑ US EPA, OCSPP (2013-02-26). "Presidential Green Chemistry Challenge: 2012 Greener Synthetic Pathways Award" (in en). https://www.epa.gov/greenchemistry/presidential-green-chemistry-challenge-2012-greener-synthetic-pathways-award.
- ↑ "Web of Science". https://www.webofscience.com/wos/woscc/basic-search.
- ↑ "Minimum Information about a Biosynthetic Gene cluster". Nature Chemical Biology 11 (9): 625–631. September 2015. doi:10.1038/nchembio.1890. PMID 26284661.
- ↑ "Enzymatic synthesis of resorcylic acid lactones by cooperation of fungal iterative polyketide synthases involved in hypothemycin biosynthesis". Journal of the American Chemical Society 132 (13): 4530–4531. April 2010. doi:10.1021/ja100060k. PMID 20222707.
- ↑ "Complete reconstitution of a highly reducing iterative polyketide synthase". Science 326 (5952): 589–592. October 2009. doi:10.1126/science.1175602. PMID 19900898.
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