Biology:2,6-dihydroxypseudooxynicotine hydrolase
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Short description: Class of enzymes
| 2,6-dihydroxypseudooxynicotine hydrolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.7.1.19 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
2,6-dihydroxypseudooxynicotine hydrolase (EC 3.7.1.19) is an enzyme with systematic name 1-(2,6-dihydroxypyridin-3-yl)-4-(methylamino)butan-1-one hydrolase.[1][2] This enzyme catalyses the following chemical reaction
- 1-(2,6-dihydroxypyridin-3-yl)-4-(methylamino)butan-1-one + H2O 2,6-dihydroxypyridine + 4-methylaminobutanoate
The enzyme is present in the soil bacterium Arthrobacter nicotinovorans.
References
- ↑ "The bacterial oxidation of nicotine. VI. The metabolism of 2,6-dihydroxypseudooxynicotine". The Journal of Biological Chemistry 240 (9): 3669–74. September 1965. PMID 5835946.
- ↑ "An alpha/beta-fold C--C bond hydrolase is involved in a central step of nicotine catabolism by Arthrobacter nicotinovorans". Journal of Bacteriology 187 (24): 8516–9. December 2005. doi:10.1128/jb.187.24.8516-8519.2005. PMID 16321959.
External links
- 2,6-dihydroxypseudooxynicotine+hydrolase at the US National Library of Medicine Medical Subject Headings (MeSH)
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