Biology:2,6-dihydroxypseudooxynicotine hydrolase

From HandWiki
Jump to: navigation, search
2,6-dihydroxypseudooxynicotine hydrolase
Identifiers
EC number3.7.1.19
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

2,6-dihydroxypseudooxynicotine hydrolase (EC 3.7.1.19) is an enzyme with systematic name 1-(2,6-dihydroxypyridin-3-yl)-4-(methylamino)butan-1-one hydrolase.[1][2] This enzyme catalyses the following chemical reaction

1-(2,6-dihydroxypyridin-3-yl)-4-(methylamino)butan-1-one + H2O [math]\rightleftharpoons[/math] 2,6-dihydroxypyridine + 4-methylaminobutanoate

The enzyme is present in the soil bacterium Arthrobacter nicotinovorans.

References

  1. "The bacterial oxidation of nicotine. VI. The metabolism of 2,6-dihydroxypseudooxynicotine". The Journal of Biological Chemistry 240 (9): 3669–74. September 1965. PMID 5835946. 
  2. "An alpha/beta-fold C--C bond hydrolase is involved in a central step of nicotine catabolism by Arthrobacter nicotinovorans". Journal of Bacteriology 187 (24): 8516–9. December 2005. doi:10.1128/jb.187.24.8516-8519.2005. PMID 16321959. 

External links





Grammarly Check DataMelt statistical framewwork for data scientists HandWiki ads