Biology:2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase

From HandWiki
Jump to: navigation, search
2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase
Identifiers
EC number3.7.1.13
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase (EC 3.7.1.13, CarC) is an enzyme with systematic name (2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate acylhydrolase.[1][2] This enzyme catalyses the following chemical reaction

(2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O [math]\rightleftharpoons[/math] anthranilate + (2E)-2-hydroxypenta-2,4-dienoate

This enzyme catalyses the third step in the aerobic degradation pathway of carbazole.

References

  1. "Purification and characterization of meta-cleavage compound hydrolase from a carbazole degrader Pseudomonas resinovorans strain CA10". Bioscience, Biotechnology, and Biochemistry 67 (1): 36–45. January 2003. doi:10.1271/bbb.67.36. PMID 12619671. 
  2. "Purification and properties of 2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,4-dienoic acid hydrolase involved in microbial degradation of carbazole". Protein Expression and Purification 28 (1): 182–9. March 2003. doi:10.1016/S1046-5928(02)00676-9. PMID 12651123. 

External links





Grammarly Check DataMelt statistical framewwork for data scientists HandWiki ads