Biology:ACTR2

Short description: Mammalian protein found in Homo sapiens

Actin-related protein 2 is a protein that in humans is encoded by the ACTR2 gene.^[1]

The specific function of ACTR2 has not yet been determined. However, it is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene.^[2]

References

↑ "The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly". J Cell Biol 138 (2): 375–84. Aug 1997. doi:10.1083/jcb.138.2.375. PMID 9230079.
↑ "Entrez Gene: ACTR2 ARP2 actin-related protein 2 homolog (yeast)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10097.

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