Biology:ARPC3

Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

ARP2/3 complex ARPC3 (21 kDa) subunit
	crystal structure of arp2/3 complex with bound adp and calcium
Identifiers
Symbol	P21-Arc
Pfam	PF04062
InterPro	IPR007204
Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

Actin-related protein 2/3 complex subunit 3 is a protein that in humans is encoded by the ARPC3 gene.^[1]^[2]^[3]

This gene encodes one of seven subunits of the Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p21 subunit, has yet to be determined.^[3]

References

↑ "The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly". J Cell Biol 138 (2): 375–84. Aug 1997. doi:10.1083/jcb.138.2.375. PMID 9230079.
↑ "Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily conserved proteins". Biochem J 328 (1): 105–12. Jan 1998. doi:10.1042/bj3280105. PMID 9359840.
↑ ^3.0 ^3.1 "Entrez Gene: ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10094.

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