Biology:Alkalihalobacillus clausii
| Alkalihalobacillus clausii | |
|---|---|
| |
| A. clausii from Enterogermina on a glass slide | |
Scientific classification 
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| Domain: | Bacteria |
| Phylum: | Bacillota |
| Class: | Bacilli |
| Order: | Bacillales |
| Family: | Bacillaceae |
| Genus: | Alkalihalobacillus |
| Species: | A. clausii
|
| Binomial name | |
| Alkalihalobacillus clausii Nielsen et al. 1995
| |
Alkalihalobacillus clausii or its old scientific name Bacillus clausii is a rod-shaped, motile, and spore-forming bacterium that lives in the soil but is also a natural microflora of the mammalian gastrointestinal tract. It is classified as probiotic microorganism that maintains a symbiotic relationship with the host organism.[1] It is currently being studied in relation to respiratory infections[2] and some gastrointestinal disorders.[3] Bacillus clausii has been found to produce antimicrobial substances that are active against gram-positive bacteria including Staphylococcus aureus, Enterococcus faecium and Clostridium difficile.[1] It is sold as an anti-diarrhoea and under the brand name Erceflora by Sanofi. [4]
This species has been recently transferred into the genus Alkalihalobacillus.[5] The correct nomenclature is thus Alkalihalobacillus clausii.
Genome structure
Alkalihalobacillus clausii has a relatively small genome that contains 4.30 Mbp with 4,108 protein coding genes.[1]
References
- ↑ 1.0 1.1 1.2 Urdaci, MC; Bressollier, P; Pinchuk, I (Jul 2004). "Bacillus clausii probiotic strains: antimicrobial and immunomodulatory activities". Journal of Clinical Gastroenterology 38 (6 Suppl): S86–90. doi:10.1097/01.mcg.0000128925.06662.69. PMID 15220667.
- ↑ "Efficacy of Bacillus clausii spores in the prevention of recurrent respiratory infections in children: a pilot study". Therapeutics and Clinical Risk Management 3 (1): 13–7. March 2007. doi:10.2147/tcrm.2007.3.1.13. PMID 18360611.
- ↑ "Bacillus clausii as a treatment of small intestinal bacterial overgrowth". The American Journal of Gastroenterology 104 (5): 1327–8. May 2009. doi:10.1038/ajg.2009.91. PMID 19352343.
- ↑ "Bacillus clausii". Monthly Index of Medical Specialities. https://www.mims.com/philippines/drug/info/bacillus%20clausii?mtype=generic.
- ↑ Patel, Sudip; Gupta, Radhey S. (2020-01-01). "A phylogenomic and comparative genomic framework for resolving the polyphyly of the genus Bacillus: Proposal for six new genera of Bacillus species, Peribacillus gen. nov., Cytobacillus gen. nov., Mesobacillus gen. nov., Neobacillus gen. nov., Metabacillus gen. nov. and Alkalihalobacillus gen. nov.". International Journal of Systematic and Evolutionary Microbiology 70 (1): 406–438. doi:10.1099/ijsem.0.003775. ISSN 1466-5026. PMID 31617837.
External links
Wikidata ☰ Q722949 entry
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