Biology:Arxiozyma heterogenica
| Arxiozyma heterogenica | |
|---|---|
Scientific classification 
| |
| Missing taxonomy template (fix): | Arxiozyma |
| Species: | Template:Taxonomy/ArxiozymaA. heterogenica
|
| Binomial name | |
| Template:Taxonomy/ArxiozymaArxiozyma heterogenica (Kurtzman & Robnett) Q.M. Wang, Yurkov & Boekhout 2024[1]
| |
| Subspecies | |
| Synonyms | |
| |
Arxiozyma heterogenica is a species of yeast from the family Saccharomycetaceae. In 2024, a commensal strain dubbed K. heterogenica var. weizmannii, isolated from mouse feces, was reported to potentially prevent opportunistic infections by Candida albicans,[3] a main causing agent of candidiasis in humans.[4]
Taxonomy
Arxiozyma heterogenica was first described as 2005 as Kazachstania heterogenica and was found to be closely related to the species in the Kazachstania telluris Complex, which was formed from several former Candida species.[5]
Ecology
In contrast to other species in the former K. telluris Complex which are usually pathogenic, commensal strains of A. heterogenica have been reported from rodents.[2] The presence of one commensal strain in the intestine of mice, originally described as K. heterogenica var. weizmannii, was shown to prevent the colonization by Candida albicans,[3] with several press reports commenting on its potential to combat infections by C. albicans ascribing these findings to a novel species named Kazachstania weizmannii.[6][7] Other complex members of K. telluris Complex are K.telluris, K.bovina, K.slooffiae, and K.pintolopesii.[8]
Subspecies
Kazachstania heterogenica var. weizmannii
Kazachstania heterogenica var. weizmannii often shortened to K.weizmannii is a member of the K.telluris complex and is thought to be a commencial strain of the K.telluris complex where most strains are usually pathogenic and is shown to prevent the colonization by Candida albicans.[8] It was isolated from murine intestines and is shown to be beneficial to mice infected by C. albicans. Due to this K.weizmannii has the potential to combat diseases like candidiasis caused by C. albicans.[9]
References
- ↑ 1.0 1.1 "Arxiozyma heterogenica". CAB International. https://www.speciesfungorum.org/Names/SynSpecies.asp?RecordID=851283.
- ↑ 2.0 2.1 "Draft genome of Kazachstania heterogenica var. weizmannii, a commensal fungus of the mouse digestive tract". Microbiology Resource Announcements 13 (4). 19 March 2024. doi:10.1128/mra.00115-24. PMID 38501775.
- ↑ 3.0 3.1 3.2 "Competitive fungal commensalism mitigates candidiasis pathology". Journal of Experimental Medicine 221 (5). May 2024. doi:10.1084/jem.20231686. PMID 38497819.
- ↑ "What Is Candida Albicans?" (in en). https://my.clevelandclinic.org/health/diseases/22961-candida-albicans.
- ↑ "Multigene Phylogenetic Analysis of Pathogenic Candida Species in the Kazachstania (Arxiozyma) telluris Complex and Description of Their Ascosporic States as Kazachstania bovina sp. nov., K. heterogenica sp. nov., K. pintolopesii sp. nov., and K. slooffiae sp. nov.". Journal of Clinical Microbiology 43 (1): 101–111. January 2005. doi:10.1128/JCM.43.1.101-111.2005. PMID 15634957.
- ↑ "Fungus vs. Fungus: Newly Identified Yeast Might Prevent Life-Threatening Fungal Infections". American Committee for the Weizmann Institute of Science (Press release). Rehovot, Israel. 18 March 2024. Retrieved 6 August 2025.
- ↑ Dyer, Rebecca (20 March 2024). "Scientists Discover a New Yeast That Might Stop Invasive Fungal Infections" (in en-US). https://www.sciencealert.com/scientists-discover-a-new-yeast-that-might-stop-invasive-fungal-infections.
- ↑ 8.0 8.1 Kralova, Jarmila Sekeresova; Fidel, Lena; Donic, Catalina; Ben-Dor, Shifra; Jung, Steffen (2024-04-11). "Draft genome of Kazachstania heterogenica var. weizmannii, a commensal fungus of the mouse digestive tract". Microbiology Resource Announcements 13 (4): e0011524. doi:10.1128/mra.00115-24. ISSN 2576-098X. PMID 38501775.
- ↑ "Rockefeller University Press". https://rupress.org/jem/article/221/5/e20231686/276637/Competitive-fungal-commensalism-mitigates.
Wikidata ☰ Q135688678 entry
 |  |
