Biology:Asialoglycoprotein
From HandWiki
Short description: Class of glycoproteins from which sialic acid has been removed by the action of sialidases
If terminal sialic acid residues are removed from glycoproteins, the resulting proteins are known as asialoglycoproteins.[1][2]
In rats, the exposure of subterminal galactose or GalNAc residues may assist in receptor-mediated endocytosis of asialoglycoproteins by asialoglycoprotein receptors on Kuppfer cells. The human ortholog of this gene is non-functional, but hepatocyte asialoglycoprotein receptors are functional in both humans and rats.[3]
External links
- Asialoglycoproteins at the US National Library of Medicine Medical Subject Headings (MeSH)
References
- ↑ Gross, Hans Jürgen; Brossmer, Reinhard (1987-06-01). "N-Acetyl-4-deoxy-d-neuraminic acid is activated and transferred on to asialoglycoprotein" (in en). Glycoconjugate Journal 4 (2): 145–156. doi:10.1007/BF01049452. ISSN 1573-4986. https://doi.org/10.1007/BF01049452.
- ↑ Regoeczi, E.; Chindemi, P. A. (1981-01-01). "The net weight of the rabbit liver and its relevance for asialoglycoprotein clearance". Growth 45 (1): 19–28. ISSN 0017-4793. PMID 7227848. https://europepmc.org/article/med/7227848.
- ↑ "Molecular characterization of the rat Kupffer cell glycoprotein receptor". Glycobiology 13 (7): 529-537. 2003. doi:10.1093/glycob/cwg068. PMID 12672702.
 |  |
