Biology:BOC (gene)
 Generic protein structure example |
Brother of CDO is a protein that in humans is encoded by the BOC gene.[1][2]
CDON (MIM 608707) and BOC are cell surface receptors of the immunoglobulin (Ig)/fibronectin type III (FNIII; see MIM 135600) repeat family involved in myogenic differentiation. CDON and BOC are coexpressed during development, form complexes with each other in a cis fashion, and are related to each other in their ectodomains, but each has a unique long cytoplasmic tail.[supplied by OMIM][2]
Interactions
BOC (gene) has been shown to interact with CDON.[1]
References
- ↑ 1.0 1.1 "BOC, an Ig superfamily member, associates with CDO to positively regulate myogenic differentiation". EMBO J 21 (1–2): 114–24. Jan 2002. doi:10.1093/emboj/21.1.114. PMID 11782431.
- ↑ 2.0 2.1 "Entrez Gene: BOC Boc homolog (mouse)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=91653.
External links
- Human BOC genome location and BOC gene details page in the UCSC Genome Browser.
Further reading
- "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791–806. 1997. doi:10.1101/gr.6.9.791. PMID 8889548.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932.
- "Promyogenic members of the Ig and cadherin families associate to positively regulate differentiation.". Proc. Natl. Acad. Sci. U.S.A. 100 (7): 3989–94. 2003. doi:10.1073/pnas.0736565100. PMID 12634428.
- "Overexpression of the immunoglobulin superfamily members CDO and BOC enhances differentiation of the human rhabdomyosarcoma cell line RD.". Mol. Carcinog. 37 (1): 1–4. 2003. doi:10.1002/mc.10121. PMID 12720294.
- "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. 2003. doi:10.1101/gr.1293003. PMID 12975309.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "Netrins and neogenin promote myotube formation.". J. Cell Biol. 167 (3): 493–504. 2004. doi:10.1083/jcb.200405039. PMID 15520228.
- "The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice.". Dev. Cell 10 (5): 647–56. 2006. doi:10.1016/j.devcel.2006.04.004. PMID 16647304.
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