Biology:Bacillus halodurans

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Bacillus halodurans is a rod-shaped, Gram-positive, motile and spore-forming bacterium found in soil. In a genomic comparison with Bacillus subtilis, B. halodurans strain C-125 - originally an unclassified Bacillus strain[1] - was found to contain unique genes and sigma factors that may have aided its adaptation to more alkaline environments.[2]

Bacteriocin production

B. halodurans produces a bacteriocin, haloduracin, that may be useful as a lantibiotic and could be produced in large quantities by solid state fermentation.[3]

Genome structure

B. halodurans has a genome that contains 4.2 Mbp with 4,066 protein coding genes.[2][4]


  1. Takami, Hideto; Horikoshi, Koki (1 January 1999). "Reidentification of Facultatively Alkaliphilic Bacillus sp. C-125 to Bacillus halodurans.". Bioscience, Biotechnology, and Biochemistry 63 (5): 943–945. doi:10.1271/bbb.63.943. PMID 27385575. 
  2. 2.0 2.1 Takami, H. (2000). "Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis". Nucleic Acids Research 28 (21): 4317–4331. doi:10.1093/nar/28.21.4317. 
  3. Danesh, A; Mamo, G; Mattiasson, B (July 2011). "Production of haloduracin by Bacillus halodurans using solid-state fermentation.". Biotechnology Letters 33 (7): 1339–44. doi:10.1007/s10529-011-0581-0. PMID 21384193. 
  4. Takami, H.; Nakasone, K.; Hirama, C.; Takaki, Y.; Masui, N.; Fuji, F.; Nakamura, Y.; Inoue, A. (Jan 1999). "An improved physical and genetic map of the genome of alkaliphilic Bacillus sp. C-125.". Extremophiles 3 (1): 21–8. doi:10.1007/s007920050095. PMID 10086841. 

External links

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