Biology:CA10
From HandWiki
Generic protein structure example |
Carbonic anhydrase-related protein 10 is an enzyme that in humans is encoded by the CA10 gene.[1][2][3]
This gene encodes a protein that belongs to the carbonic anhydrase family of zinc metalloenzymes, which catalyze the reversible hydration of carbon dioxide in various biological processes. The protein encoded by this gene is an acatalytic member of the alpha-carbonic anhydrase subgroup, and it is thought to play a role in the central nervous system, especially in brain development. Multiple transcript variants encoding the same protein have been found for this gene.[3]
References
- ↑ "Functional diversity, conservation, and convergence in the evolution of the alpha-, beta-, and gamma-carbonic anhydrase gene families". Mol Phylogenet Evol 5 (1): 50–77. Aug 1996. doi:10.1006/mpev.1996.0006. PMID 8673298.
- ↑ "CCG repeats in cDNAs from human brain". Hum Genet 103 (6): 666–73. Feb 1999. doi:10.1007/s004390050889. PMID 9921901.
- ↑ 3.0 3.1 "Entrez Gene: CA10 carbonic anhydrase X". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56934.
External links
- Human CA10 genome location and CA10 gene details page in the UCSC Genome Browser.
Further reading
- "Carbonic anhydrase inhibitors.". Med Res Rev 23 (2): 146–89. 2003. doi:10.1002/med.10025. PMID 12500287.
- "Designing of novel carbonic anhydrase inhibitors and activators.". Curr Med Chem Cardiovasc Hematol Agents 2 (1): 49–68. 2005. doi:10.2174/1568016043477305. PMID 15328829.
- "Carbonic anhydrases: current state of the art, therapeutic applications and future prospects.". J Enzyme Inhib Med Chem 19 (3): 199–229. 2004. doi:10.1080/14756360410001689540. PMID 15499993.
- "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. 2001. doi:10.1101/gr.GR1547R. PMID 11230166.
- "cDNA sequence of human carbonic anhydrase-related protein, CA-RP X: mRNA expressions of CA-RP X and XI in human brain.". Biochim. Biophys. Acta 1518 (3): 311–6. 2001. doi:10.1016/s0167-4781(01)00193-2. PMID 11311946.
- "Developmental expression of carbonic anhydrase-related proteins VIII, X, and XI in the human brain.". Neuroscience 112 (1): 93–9. 2002. doi:10.1016/S0306-4522(02)00066-0. PMID 12044474.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. 2003. doi:10.1101/gr.1293003. PMID 12975309.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. 2006. doi:10.1101/gr.4039406. PMID 16344560.
- "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. 2006. doi:10.1016/j.cell.2006.09.026. PMID 17081983.