Biology:CAP1
From HandWiki
 Generic protein structure example |
Adenylyl cyclase-associated protein 1 is an enzyme that in humans is encoded by the CAP1 gene.[1][2][3]
The protein encoded by this gene is related to the S. cerevisiae CAP protein, which is involved in the cyclic AMP pathway. The human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin.[3]
Interactions
CAP1 has been shown to interact with ACTG1[4] and CAP2.[2]
References
- ↑ "Identification of a human cDNA encoding a protein that is structurally and functionally related to the yeast adenylyl cyclase-associated CAP proteins". Mol Cell Biol 12 (11): 5033–40. Nov 1992. doi:10.1128/mcb.12.11.5033. PMID 1406678.
- ↑ 2.0 2.1 "Mammalian CAP interacts with CAP, CAP2, and actin". J Cell Biochem 61 (3): 459–66. Apr 1997. doi:10.1002/(SICI)1097-4644(19960601)61:3<459::AID-JCB13>3.0.CO;2-E. PMID 8761950.
- ↑ 3.0 3.1 "Entrez Gene: CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10487.
- ↑ Hubberstey, A; Yu G; Loewith R; Lakusta C; Young D (Jun 1996). "Mammalian CAP interacts with CAP, CAP2, and actin". J. Cell. Biochem. (UNITED STATES) 61 (3): 459–66. doi:10.1002/(SICI)1097-4644(19960601)61:3<459::AID-JCB13>3.0.CO;2-E. ISSN 0730-2312. PMID 8761950.
External links
- Human CAP1 genome location and CAP1 gene details page in the UCSC Genome Browser.
Further reading
- "Comparison of human CAP and CAP2, homologs of the yeast adenylyl cyclase-associated proteins". J. Cell Sci. 107 (6): 1671–8. 1994. PMID 7962207.
- "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. 1994. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. 1997. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- "Human CAP1 is a key factor in the recycling of cofilin and actin for rapid actin turnover". J. Cell Sci. 115 (Pt 8): 1591–601. 2003. PMID 11950878.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. 21 (5): 566–9. 2004. doi:10.1038/nbt810. PMID 12665801.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "Crystal structure of the actin binding domain of the cyclase-associated protein". Biochemistry 43 (33): 10628–41. 2004. doi:10.1021/bi049071r. PMID 15311924.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R.
- "The identification of myocilin-associated proteins in the human trabecular meshwork". Exp. Eye Res. 82 (6): 1046–52. 2006. doi:10.1016/j.exer.2005.09.016. PMID 16289162.
- "Transcriptome analysis of human gastric cancer". Mamm. Genome 16 (12): 942–54. 2006. doi:10.1007/s00335-005-0075-2. PMID 16341674.
- "The DNA sequence and biological annotation of human chromosome 1". Nature 441 (7091): 315–21. 2006. doi:10.1038/nature04727. PMID 16710414. Bibcode: 2006Natur.441..315G.
- "Phosphoproteomic analysis of the human pituitary". Pituitary 9 (2): 109–20. 2006. doi:10.1007/s11102-006-8916-x. PMID 16807684.
- "The clinical significance of the spectrum of interactions of CAP+1 (A-->C), a silent beta-globin gene mutation, with other beta-thalassemia mutations and globin gene modifiers in north Indians". Eur. J. Haematol. 79 (5): 417–21. 2007. doi:10.1111/j.1600-0609.2007.00958.x. PMID 17900295.
PDB gallery | |
|---|---|
|
 |
