Biology:CHSY1
From HandWiki
 Generic protein structure example |
Chondroitin sulfate synthase 1 is an enzyme that in humans is encoded by the CHSY1 gene.[1][2]
CHSY1 synthesizes chondroitin sulfate, a glycosaminoglycan expressed on the surface of most cells and in extracellular matrices. Glycosaminoglycan chains are covalently linked to a wide range of core protein families and regulate many biologic processes, including cell proliferation and recognition, extracellular matrix deposition, and morphogenesis.[3][2]
References
- ↑ "Molecular cloning and expression of a human chondroitin synthase". J Biol Chem 276 (42): 38721–6. Oct 2001. doi:10.1074/jbc.M106871200. PMID 11514575.
- ↑ 2.0 2.1 "Entrez Gene: CHSY1 carbohydrate (chondroitin) synthase 1". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22856.
- ↑ supplied by OMIM
External links
- Human CHSY1 genome location and CHSY1 gene details page in the UCSC Genome Browser.
Further reading
- "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117–26. 2007. doi:10.1093/dnares/12.2.117. PMID 16303743.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. 2003. doi:10.1101/gr.1293003. PMID 12975309.
- "Chondroitin sulfate synthase-3. Molecular cloning and characterization.". J. Biol. Chem. 278 (41): 39711–25. 2003. doi:10.1074/jbc.M304421200. PMID 12907687.
- "Molecular cloning of a chondroitin polymerizing factor that cooperates with chondroitin synthase for chondroitin polymerization.". J. Biol. Chem. 278 (26): 23666–71. 2003. doi:10.1074/jbc.M302493200. PMID 12716890.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 6 (1): 63–70. 1999. doi:10.1093/dnares/6.1.63. PMID 10231032.
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