Biology:DGCR5
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In molecular biology, DiGeorge syndrome critical region gene 5 (non-protein coding), also known as DGCR5, is a long non-coding RNA. In humans, it is located on chromosome 22q11, at the ADU breakpoint associated with DiGeorge syndrome.[1] Its expression is regulated by the transcription factor REST (RE1-Silencing Transcription factor).[2]
See also
- Long noncoding RNA
References
- ↑ "Identification of a novel transcript disrupted by a balanced translocation associated with DiGeorge syndrome". American Journal of Human Genetics 59 (1): 23–31. Jul 1996. PMID 8659529.
- ↑ "Regulation of neural macroRNAs by the transcriptional repressor REST". RNA 15 (1): 85–96. Jan 2009. doi:10.1261/rna.1127009. PMID 19050060.
Further reading
- "Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping". DNA Research 8 (1): 1–9. Feb 2001. doi:10.1093/dnares/8.1.1. PMID 11258795.
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