Biology:DIP2B
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
DIP2 disco-interacting protein 2 homolog B (Drosophila) is a protein that in humans is encoded by the DIP2B gene.[1] A member of the disco-interacting protein homolog 2 protein family, it contains a binding site for the transcriptional regulator DNA methyltransferase 1 associated protein 1, as well as AMP-binding sites. The presence of these sites suggests that DIP2B may participate in DNA methylation. This gene is located near a folate-sensitive fragile site.[1][2]
References
- ↑ 1.0 1.1 "DIP2 disco-interacting protein 2 homolog B (Drosophila)". https://www.ncbi.nlm.nih.gov/gene/57609.
- ↑ Winnepenninckx, B.; Debacker, K.; Ramsay, J.; Smeets, D.; Smits, A.; Fitzpatrick, D. R.; Kooy, R. F. (2007). "CGG-Repeat Expansion in the DIP2B Gene is Associated with the Fragile Site FRA12A on Chromosome 12q13.1". The American Journal of Human Genetics 80 (2): 221–231. doi:10.1086/510800. PMID 17236128.
Further reading
- Houlston, R. S.; Cheadle, J.; Dobbins, S. E.; Tenesa, A.; Jones, A. M.; Howarth, K.; Spain, S. L.; Broderick, P. et al. (2010). "Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33". Nature Genetics 42 (11): 973–977. doi:10.1038/ng.670. PMID 20972440.
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